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Referencia número: HY-W728761

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Voxelotor-d₇

Name: Voxelotor-d7
Brand: MedChemExpress
SKU: HY-W728761
Availability: PreOrder

(Synonyms: GBT 440-d₇)

Voxelotor-d7 is the deuterium labeled Voxelotor (HY-18681). Voxelotor is a potent inhibitor of haemoglobin S (HbS) polymerization.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₁₉H₁₂D₇N₃O₃
Peso molecular:344.42

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Voxelotor-d₇ Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Aplicación
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

Voxelotor-d7 is the deuterium labeled Voxelotor (HY-18681). Voxelotor is a potent inhibitor of haemoglobin S (HbS) polymerization^[1].

Aplicación

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Peso molecular 344.42
Fòrmula C₁₉H₁₂D₇N₃O₃
SMILES

[2H]C([2H])(C(N1N=CC=C1C2=NC=CC=C2COC3=C(C(O)=CC=C3)C=O)(C([2H])([2H])[2H])[2H])[2H]
Synonyms

GBT 440-d₇
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Oksenberg D, et al. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease. Br J Haematol. 2016 Oct;175(1):141-53. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Voxelotor-d7

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Voxelotor-d7 Related Classifications

HY-W728761 Related Classifications

Bioz

Voxelotor-d₇

Voxelotor-d₇ Related Classifications