2. Gene
  3. TUBGCP5 - tubulin gamma complex associated protein 5 Gene

TUBGCP5 - tubulin gamma complex associated protein 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GCP5

Gene ID: 114791 | Gene type: protein coding

About TUBGCP5

Cytogenetic location: 15q11.2 Genomic coordinates (GRCh38): 15:22,983,025-23,039,569 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 205 orthologues and 4 paralogues. Ubiquitous expression in testis (RPKM 5.8), brain (RPKM 3.5) and 25 other tissues.

Summary

Enables microtubule binding activity. Involved in microtubule nucleation. Located in centrosome and cytosol. Part of gamma-tubulin large complex. [provided by Alliance of Genome Resources, Apr 2022]

TUBGCP5 Products(9)

mRNA Protein Name
NM_001102610.2 NP_001096080.1 gamma-tubulin complex component 5 isoform b
NM_001354372.2 NP_001341301.1 gamma-tubulin complex component 5 isoform c
NM_001354373.2 NP_001341302.1 gamma-tubulin complex component 5 isoform d
NM_001354374.2 NP_001341303.1 gamma-tubulin complex component 5 isoform e
NM_001354375.2 NP_001341304.1 gamma-tubulin complex component 5 isoform f
NM_001354376.2 NP_001341305.1 gamma-tubulin complex component 5 isoform g
NM_001354377.2 NP_001341306.1 gamma-tubulin complex component 5 isoform h
NM_001354378.2 NP_001341307.1 gamma-tubulin complex component 5 isoform i
NM_052903.6 NP_443135.3 gamma-tubulin complex component 5 isoform a

TUBGCP5 Protein Structure

Spc97_Spc98

Spc97_Spc98: Spc97 / Spc98 family (273 - 942)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1024 a.a.
Protein Preferred Names Protein Names

gamma-tubulin complex component 5

gamma-tubulin complex component GCP5

Related Diseases

Diseases Alias
Cataract 25

Cataract, Central Saccular, With Sutural Opacities

CTRCT25

Ccsso

Cataract, Central Pouch-Like, With Sutural Opacities

Central Pouch-Like Cataract With Sutural Opacities

Central Saccular Cataract With Sutural Opacities

Early-Onset Cataract With Y-Shaped Suture Opacities
Spastic Paraplegia 6, Autosomal Dominant

SPG6

Fsp3

Hereditary Spastic Paraplegia 6

Autosomal Dominant Spastic Paraplegia Type 6

Spastic Paraplegia 6

Familial Spastic Paraplegia Autosomal Dominant 3

Familial Spastic Paraplegia, Autosomal Dominant, 3

Autosomal Dominant Familial Spastic Paraplegia Type 3

Autosomal Dominant Spastic Paraplegia 6

Spastic Paraplegia-6

Paraplegia, Spastic, Type 6
Angelman Syndrome

AS

Happy Puppet Syndrome

Happy Puppet Syndrome, Formerly

Puppetlike Syndrome
Chromosome 15q11.2 Deletion Syndrome

15q11.2 Microdeletion Syndrome

15q11.2 Bp1-Bp2 Microdeletion Syndrome

Del(15)(Q11.2)

Monosomy 15q11.2

15q11.2 Microdeletion

Chromosome 15q11.2 Deletion

Chromosome 15q11.2 Microdeletion

Chromosome Deletion Syndrome 15q11.2

Microdeletion 15q11.2

Duplication 15q11-Q13 Syndrome
Dyscalculia

Disorder Of Arithmetical Skills

Mathematics Disorder

Developmental Arithmetic Disorder
Prader-Willi Syndrome

Prader-Labhart-Willi Syndrome

PWS

Willi-Prader Syndrome

Prader-Willi Syndrome Due To Translocation

Prader-Willi Syndrome Due To Imprinting Mutation

Prader-Willi Syndrome Due To Maternal Uniparental Disomy Of Chromosome 15

Prader Willi Syndrome

Upd(15)Mat
Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations

MCCCHCM
Precocious Puberty, Central, 2

CPPB2

Central Precocious Puberty 2

Precocious Puberty, Central 2

Precocious Puberty, Central, Type 2
Reading Disorder

Specific Reading Disorder

Reading

Dyslexia

Developmental Reading Disorder
Childhood Absence Epilepsy

Pyknolepsy

Petit Mal Epilepsy

Absence Seizures

Absence Seizure

Petit Mal Seizure

Absence Epilepsy, Childhood

Pykno-Epilepsy

Epilepsy, Absence

Absence Epilepsy

Pycnolepsy
Dyslexia
Hereditary Spastic Paraplegia

Familial Spastic Paraplegia

Hereditary Spastic Paraparesis

Strumpell-Lorrain Disease

Familial Spastic Paraparesis

Hsp

Spg

Strümpell-Lorrain Disease

Spastic Paraplegia, Hereditary

French Settlement Disease

Strumpell-Lorrain Syndrome

Fsp

Spastic Paraplegia, Familial

Spastic Paraplegia Hereditary

Spastic Paraplegia 3, Autosomal Dominant

Spastic Paraparesis

Hereditary Spastic Paralysis

Familial Spastic Paralysis

Hereditary Spastic Ataxia
Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity
Primary Autosomal Recessive Microcephaly

Autosomal Recessive Primary Microcephaly

Mcph

True Microcephaly

Microcephalia Vera

Microcephaly Vera

Microcephaly Primary Hereditary

Microcephaly, Primary, Autosomal Recessive

Primary Microcephaly
Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15265 TUBGCP5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta TUBGCP5 VGNC VGNC:79155
Bos taurus TUBGCP5 VGNC VGNC:36515
Rattus norvegicus TUBGCP5 RGD RGD:1304689
Mus musculus TUBGCP5 MGD MGI:2178836
Canis familiaris TUBGCP5 VGNC VGNC:47995
Felis catus TUBGCP5 VGNC VGNC:66707