CYLD - CYLD lysine 63 deubiquitinase Gene

Also Known as EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLD1; CYLDI; USPL2; FTDALS8

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1540

About CYLD

Cytogenetic location: 16q12.1 Genomic coordinates (GRCh38): 16:50,742,086-50,801,935 (from NCBI)

This gene has 15 transcripts (splice variants), 212 orthologues and is associated with 82 phenotypes. Ubiquitous expression in bone marrow (RPKM 13.0), lymph node (RPKM 10.5) and 25 other tissues.

Summary

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

CYLD Products (16)

mRNA Protein Name
NM_001042355.2 NP_001035814.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
NM_001042412.3 NP_001035877.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
NM_001378743.1 NP_001365672.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 1
NM_001378744.1 NP_001365673.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
NM_001378745.1 NP_001365674.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
NM_001378746.1 NP_001365675.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
NM_001378747.1 NP_001365676.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
NM_001378748.1 NP_001365677.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
NM_001378749.1 NP_001365678.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
NM_001378750.1 NP_001365679.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
NM_001378751.1 NP_001365680.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 3
NM_001378752.1 NP_001365681.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 3
NM_001378753.1 NP_001365682.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 3
NM_001378754.1 NP_001365683.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 4
NM_001378755.1 NP_001365684.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 4
NM_015247.3 NP_056062.1 ubiquitin carboxyl-terminal hydrolase CYLD isoform 1
Molecular Function GO Annotation Evidence References Source
enables K63-linked deubiquitinase activity EXP
EXP: Inferred from Experiment
26997266 GOA
enables K63-linked deubiquitinase activity IDA
IDA: Inferred from direct assay
18313383 GOA
enables Met1-linked polyubiquitin deubiquitinase activity EXP
EXP: Inferred from Experiment
26997266 GOA
enables cysteine-type deubiquitinase activity IDA
IDA: Inferred from direct assay
18313383 GOA
enables proline-rich region binding IPI
IPI: Inferred from physical interaction
15341735 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
18636086 GOA
enables protein kinase binding IPI
IPI: Inferred from physical interaction
17495026 GOA
enables zinc ion binding IDA
IDA: Inferred from direct assay
18313383 GOA
Biological Process GO Annotation Evidence References Source
involved in innate immune response IDA
IDA: Inferred from direct assay
26997266 GOA
involved in negative regulation of JNK cascade IDA
IDA: Inferred from direct assay
29291351 GOA
involved in negative regulation of NF-kappaB transcription factor activity IDA
IDA: Inferred from direct assay
18313383 GOA
involved in negative regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
20227366 GOA
involved in negative regulation of non-canonical NF-kappaB signal transduction IDA
IDA: Inferred from direct assay
18313383 GOA
involved in negative regulation of p38MAPK cascade IDA
IDA: Inferred from direct assay
29291351 GOA
involved in positive regulation of extrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
21525013 GOA
involved in protein deubiquitination IDA
IDA: Inferred from direct assay
29291351 GOA
involved in protein linear deubiquitination IDA
IDA: Inferred from direct assay
26997266 GOA
involved in regulation of inflammatory response IDA
IDA: Inferred from direct assay
27591049 GOA
involved in regulation of intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
21525013 GOA
involved in regulation of microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
20194890 GOA
involved in regulation of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
17495026 GOA
involved in regulation of necroptotic process IDA
IDA: Inferred from direct assay
27458237 GOA
involved in regulation of tumor necrosis factor-mediated signaling pathway IDA
IDA: Inferred from direct assay
26997266 GOA
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
25134987 GOA
colocalizes with cytoplasmic microtubule IDA
IDA: Inferred from direct assay
17495026 GOA
colocalizes with cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
20194890 GOA
located in cytosol IDA
IDA: Inferred from direct assay
18313383 GOA
colocalizes with midbody IDA
IDA: Inferred from direct assay
17495026 GOA
located in spindle IDA
IDA: Inferred from direct assay
25134987 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CYLD Protein Structure

CAP_GLY

CAP_GLY: CAP-Gly domain (127 - 202)

CAP_GLY

CAP_GLY: CAP-Gly domain (232 - 290)

CAP_GLY

CAP_GLY: CAP-Gly domain (469 - 536)

UCH

UCH: Ubiquitin carboxyl-terminal hydrolase (590 - 886)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 953 a.a.
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase CYLD

  • cylindromatosis (turban tumor syndrome)

CYLD Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CYLD Q9NQC7 ITCH Homo sapiens Q96J02 22057290
Intra
CYLD Q9NQC7 HDAC6 Homo sapiens Q9UBN7 19893491
Intra
CYLD Q9NQC7 TUBA1A Homo sapiens Q71U36 19893491
Intra
CYLD Q9NQC7 TUBA1A Homo sapiens Q71U36 19893491
Intra
CYLD Q9NQC7 ITCH Homo sapiens Q96J02-2 22057290
Intra
CYLD Q9NQC7 SPATA2 Homo sapiens Q9UM82 19615732
Intra
CYLD Q9NQC7 SPATA2 Homo sapiens Q9UM82
TAP
24981860
Intra
CYLD Q9NQC7 RIGI Homo sapiens O95786 18636086
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Brooke-Spiegler Syndrome
  • Cyld Cutaneous Syndrome

  • Spiegler-Brooke Syndrome

  • Familial Cylindromatosis

  • BRSS

  • Bss

  • Sbs

  • Multiple Familial Trichoepithelioma

  • Ancell-Spiegler Cylindromas

  • Familial Multiple Trichoepithelioma

  • Trichoepithelioma

  • Fc

  • Mft

  • Multiple Familial Trichoepitheliomas

  • Ccs

  • Turban Tumor Syndrome

  • Schilbach-Rott Syndrome

  • Eccrine Dermal Cylindroma

  • Familial Multiple Trichoepitheliomata

Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 8
  • FTDALS8

Trichoepithelioma, Multiple Familial, 1
  • Epithelioma Adenoides Cysticum Of Brooke

  • MFT1

  • Eac

  • Brooke-Fordyce Trichoepitheliomas

  • Epithelioma, Hereditary Multiple Benign Cystic

  • Multiple Familial Trichoepithelioma 1

  • Hereditary Multiple Benign Cystic Epithelioma

  • Familial Multiple Trichoepitheliomata

Cylindromatosis, Familial
  • Ancell-Spiegler Cylindromas

  • 'Turban Tumor' Syndrome

  • Cylindromas, Dermal Eccrine

  • Dermal Eccrine Cylindroma

  • FCYL

  • Dermal Eccrine Cylindromatosis

  • Turban Tumor Syndrome

  • Eccrine Dermal Cylindroma

Spiradenoma
  • Eccrine Spiradenoma

  • Benign Eccrine Spiradenoma

  • Eccrine Spiradenoma Of Skin

  • Es

  • Eccrine Spiradenoma, Benign

Apocrine Sweat Gland Neoplasm
  • Apocrine Tumor

  • Apocrine Neoplasm

Plasma Cell Neoplasm
  • Plasma Cell Dyscrasia

  • Paraproteinemias

  • Plasma Cell Tumour

  • Plasmacytic Tumor

  • Multiple Myeloma

  • Plasmacytoma

  • Plasma Cell Tumours

  • Plasma Cells Dyscrasia

Epidermal Appendage Tumor
  • Neoplasm Of Skin With Adnexal Differentiation

  • Neoplasm Of The Skin Appendage

  • Skin Appendage Tumour

Anus Basaloid Carcinoma
  • Basaloid Carcinoma Of The Anus

  • Anal Basaloid Carcinoma

Amyotrophic Lateral Sclerosis 8
  • Amyotrophic Lateral Sclerosis Type 8

  • ALS8

  • Sclerosis, Lateral, Amyotrophic, Type Type 8

Salivary Gland Carcinoma
  • Salivary Gland Cancer

  • Malignant Neoplasm Of Salivary Gland

  • Salivary Gland Neoplasms

Malignant Spiradenoma
  • Malignant Eccrine Spiradenoma

  • Eccrine Spiradenoma, Malignant

  • Mes

Basal Cell Carcinoma
  • Basal Cell Cancer

  • Basal Cell Neoplasm

  • Basal Cell Carcinoma Of Skin

  • Malignant Basal Cell Tumor

  • Basal Cell Tumor

  • Epithelioma Basal Cell

  • Malignant Basal Cell Neoplasm

  • Rodent Ulcer

  • Carcinoma Basal Cell

  • Neoplasms, Basal Cell

  • Basal Cell Carcinomas

  • Experimental Organism Basal Cell Carcinoma

  • Nodulo-Ulcerative Basal Cell Carcinoma

  • Basalioma

  • Basal Cell Epithelioma Of Skin

  • Bcc - [Basal Cell Carcinoma] Of Skin

  • Rodent Ulcer Of Skin

  • Rodent Ulcer Of Unspecified Site

  • Basal Cell Epithelioma Of Unspecified Site

Salivary Gland Adenoid Cystic Carcinoma
  • Cylindroma

Myeloma, Multiple
  • Multiple Myeloma

  • Plasma Cell Myeloma

  • Kahler Disease

  • Myelomatosis

  • Medullary Plasmacytoma

  • Multiple Myeloma, Resistance To

  • Myeloma

  • Plasma Cell Dyscrasia

  • Kahler'S Disease

  • Multiple Myeloma, Susceptibility To

  • Myeloma - Multiple

  • Kahler-Bozzolo Disease

  • Plasma Cell Myelomas

  • MM

  • Plasma Cell Neoplasm

  • Primary Systemic Amyloidosis

  • Primary Amyloidosis

  • Immunoglobulin Deposition Disease

  • Plasmacytic Myeloma

  • Multiple Myelomata

  • Multiple Myeloma Nos

  • Multiple Myeloma Without Mention Of Remission

  • Monostotic Plasma Cell Myeloma

  • Mm - [Multiple Myeloma]

Sweat Gland Benign Neoplasm
  • Neoplasm Of Sweat Gland

  • Sweat Gland Tumor

  • Tumor Of The Sweat Gland

  • Sweat Gland Neoplasms

  • Sweat Gland Neoplasm

Osteonecrosis Of The Jaw
Frontotemporal Dementia
  • Pallidopontonigral Degeneration

  • Frontotemporal Lobar Degeneration

  • Semantic Dementia

  • FTD

  • Frontotemporal Lobe Dementia

  • Multiple System Tauopathy With Presenile Dementia

  • Dementia, Frontotemporal

  • Frontotemporal Dementia With Parkinsonism

  • Mstd

  • Frontotemporal Lobar Degeneration With Tau Inclusions

  • Ftld With Tau Inclusions

  • Dementia, Frontotemporal, With Parkinsonism

  • Fldem

  • Ftdp17

  • Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex

  • Ddpac

  • Wilhelmsen-Lynch Disease

  • Wld

  • Ppnd

  • Dementia, Frontotemporal, With Or Without Parkinsonism

  • Semantic Primary Progressive Aphasia

  • Semantic Variant Ppa

  • Wilhemsen-Lynch Disease

  • Frontotemporal Dementia-Amyotrophic Lateral Sclerosis

  • Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17

  • Ftd-Als

  • Ftld

  • Pick Complex

  • Pick Disease Of The Brain

  • Frontotemporal Dementia With Parkinsonism-17

  • Grn-Related Frontotemporal Dementia

  • Frontotemporal Dementia With Motor Neuron Disease

  • Dementia In Fronto-Temporal Lobar Degeneration

  • Ftd - [Frontotemporal Dementia]

  • Temple Dementia

  • Frontal Lobe Dementia

Adenoid Cystic Carcinoma
  • Adenocystic Carcinoma

  • Cribriform Carcinoma

  • Cylindroma

  • Carcinoma Adenoid Cystic

  • Carcinoma, Adenoid Cystic

  • Adenoid Cystic Carcinoma Of Salivary Gland

  • Eccrine Dermal Cylindroma

  • Carcinoma, Cribriform

Salivary Gland Disease
  • Salivary Gland Disorders

  • Salivary Gland Diseases

  • Non-Neoplastic Salivary Gland Disease

  • Non-Neoplastic Salivary Gland Disorder

  • Disorder Of Salivary Gland

  • Lesion Of Salivary Gland Nos

Dementia
  • Dementias

  • Presenile Dementia

  • Alzheimer Type Dementia

  • Alzheimer Sclerosis

  • Alzheimer Disease Dementia

  • Alzheimer Dementia

  • Primary Degenerative Alzheimer Type Dementia

  • End Stage Alzheimer'S Dementia

  • Alzheimer'S Type Atypical Dementia

  • Alzheimer Type Presenile Dementia

  • Early Onset Alzheimer Dementia

  • Dementia In Alzheimer Disease Type 2

  • Dementia In Alzheimer Disease With Early Onset

  • Early Onset Alzheimer Type Dementia, Uncomplicated

  • Primary Degenerative Alzheimer Type Dementia, Early Onset

  • Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated

  • Alzheimer Disease Dementia With Early Onset

  • Presenile Sclerosis

  • Presenile Brain Sclerosis

  • Presenile Alzheimer Brain Sclerosis

  • Late Onset Alzheimer Dementia

  • Dementia In Alzheimer Disease Type 1

  • Dementia In Alzheimer Disease With Late Onset

  • Primary Degenerative Alzheimer Type Dementia, Late Onset

  • Sdat - [Senile Dementia, Alzheimer Type]

  • Alzheimer Disease Dementia With Late Onset

  • Late Onset Alzheimer Brain Sclerosis

  • Senile Alzheimer Brain Disease

  • Senile Alzheimer Brain Sclerosis

  • Senile Primary Degenerative Alzheimer Type Dementia

  • Senile Dementia Of The Alzheimer Type

  • Arteriosclerotic Dementia

  • Strategic-Infarct Dementia

  • Post Stroke Dementia

  • Vascular Cognitive Impairment

  • Vascular Dementia

  • Dementia Of The Lewy Body Type

  • Dementia With Lewy Bodies

  • Sdlt - [Senile Dementia Of The Lewy Body Type]

  • Senile Dementia Of The Lewy Body Type

  • Alcohol-Related Dementia

  • Alcoholic Dementia Nos

  • Alcohol-Induced Dementia

  • Alcoholic Brain Syndrome

  • Chronic Alcoholic Brain Syndrome

  • Alcohol Dementia

  • Late Onset Alcoholic Psychosis

  • Residual And Late-Onset Alcohol-Induced Psychotic Disorder

  • Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder

  • Late-Onset Psychoactive Substance-Induced Psychotic Disorder

  • Inhalant Dementia

  • Volatile Solvents Dementia

  • Dementia In Paralysis Agitans

  • Pdd - [Parkinson Disease Dementia]

  • Dementia Syndrome Of Parkinson Disease

  • Dementia In Parkinson Disease

  • Parkinson Related Dementia

  • Dementia In Huntington Chorea

  • Hiv - [Human Immunodeficiency Virus] Dementia

  • Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex

  • Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex

  • Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex

  • Aids Related Dementia

  • Dementia Due To Niacin Deficiency

Autoinflammation, Panniculitis, And Dermatosis Syndrome
  • Otulipenia

  • Otulin-Related Autoinflammatory Syndrome

  • AIPDS

  • Oras

  • Infantile-Onset Periodic Fever-Panniculitis-Dermatosis Syndrome

  • Autoinflammation, Panniculitis And Dermatosis Syndrome

  • Otulin Deficiency

Sweat Gland Disease
  • Sweat Gland Diseases

Bartholin'S Gland Adenoid Cystic Carcinoma
  • Bartholin Gland Adenoid Cystic Carcinoma

Eccrine Adenocarcinoma
Glycogen Storage Disease Iv
  • Gsd Iv

  • Glycogen Branching Enzyme Deficiency

  • Andersen Disease

  • Amylopectinosis

  • Glycogen Storage Disease Type Iv

  • GSD4

  • Brancher Deficiency

  • Glycogen Storage Disease, Type Iv

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Congenital Neuromuscular Form

  • Gbe1 Deficiency

  • Glycogenosis Iv

  • Cirrhosis, Familial, With Deposition Of Abnormal Glycogen

  • Glycogen Storage Disease Type 4

  • Glycogenosis 4

  • Potassium-Sensitive Periodic Paralysis, Ventricular Ectopy, And Dysmorphic Features

  • Andersen'S Disease

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Childhood Neuromuscular Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Fatal Perinatal Neuromuscular Form

  • Brancher Deficiency Glycogenosis

  • Branching-Transferase Deficiency Glycogenosis

  • Deficiency Of 1,4-Alpha-Glucan Branching Enzyme

  • Andersen-Tawil Syndrome

  • Gsd 4

  • Andersen Cardiodysrhythmic Periodic Paralysis

  • Lqt7

  • Long Qt Syndrome 7

  • Periodic Paralysis, Potassium-Sensitive Cardiodysrhythmic Type

  • Andersen Glycogenosis

  • Branching Enzyme Deficiency

  • Glycogenosis, Type Iv

  • Gsd Type Iv

  • Type Iv Glycogenosis

  • Gbe Deficiency, Childhood Neuromuscular Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Childhood Neuromuscular Form

  • Gsd Type 4, Childhood Neuromuscular Form

  • Gsdiv, Childhood Neuromuscular Form

  • Glycogen Storage Disease Type 4, Childhood Neuromuscular Form

  • Glycogen Storage Disease Type Iv, Childhood Neuromuscular Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Childhood Neuromuscular Form

  • Glycogenosis Type 4, Childhood Neuromuscular Form

  • Glycogenosis Type Iv, Childhood Neuromuscular Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Adult Neuromuscular Form

  • Gbe Deficiency, Adult Neuromuscular Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Adult Neuromuscular Form

  • Gsd Type 4, Adult Neuromuscular Form

  • Gsdiv, Adult Neuromuscular Form

  • Glycogen Storage Disease Type 4, Adult Neuromuscular Form

  • Glycogen Storage Disease Type Iv, Adult Neuromuscular Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Adult Neuromuscular Form

  • Glycogenosis Type 4, Adult Neuromuscular Form

  • Glycogenosis Type Iv, Adult Neuromuscular Form

  • Gbe Deficiency, Congenital Neuromuscular Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Congenital Neuromuscular Form

  • Gsd Type 4, Congenital Neuromuscular Form

  • Gsdiv, Congenital Neuromuscular Form

  • Glycogen Storage Disease Type 4, Congenital Neuromuscular Form

  • Glycogen Storage Disease Type Iv, Congenital Neuromuscular Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Congenital Neuromuscular Form

  • Glycogenosis Type 4, Congenital Neuromuscular Form

  • Glycogenosis Type Iv, Congenital Neuromuscular Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Childhood Combined Hepatic And Myopathic Form

  • Gbe Deficiency, Childhood Combined Hepatic And Myopathic Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Childhood Combined Hepatic And Myopathic Form

  • Gsd Type 4, Childhood Combined Hepatic And Myopathic Form

  • Gsdiv, Childhood Combined Hepatic And Myopathic Form

  • Glycogen Storage Disease Type 4, Childhood Combined Hepatic And Myopathic Form

  • Glycogen Storage Disease Type Iv, Childhood Combined Hepatic And Myopathic Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Childhood Combined Hepatic And Myopathic Form

  • Glycogenosis Type 4, Childhood Combined Hepatic And Myopathic Form

  • Glycogenosis Type Iv, Childhood Combined Hepatic And Myopathic Form

  • Gbe Deficiency, Fatal Perinatal Neuromuscular Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Fatal Perinatal Neuromuscular Form

  • Gsd Type 4, Fatal Perinatal Neuromuscular Form

  • Gsdiv, Fatal Perinatal Neuromuscular Form

  • Glycogen Storage Disease Type 4, Fatal Perinatal Neuromuscular Form

  • Glycogen Storage Disease Type Iv, Fatal Perinatal Neuromuscular Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Fatal Perinatal Neuromuscular Form

  • Glycogenosis Type 4, Fatal Perinatal Neuromuscular Form

  • Glycogenosis Type Iv, Fatal Perinatal Neuromuscular Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Non Progressive Hepatic Form

  • Gbe Deficiency, Non Progressive Hepatic Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Non Progressive Hepatic Form

  • Gsd Type 4, Non Progressive Hepatic Form

  • Gsdiv, Non Progressive Hepatic Form

  • Glycogen Storage Disease Type 4, Non Progressive Hepatic Form

  • Glycogen Storage Disease Type Iv, Non Progressive Hepatic Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Non Progressive Hepatic Form

  • Glycogenosis Type 4, Non Progressive Hepatic Form

  • Glycogenosis Type Iv, Non Progressive Hepatic Form

  • Glycogen Storage Disease Due To Glycogen Branching Enzyme Deficiency, Progressive Hepatic Form

  • Gbe Deficiency, Progressive Hepatic Form

  • Gsd Due To Glycogen Branching Enzyme Deficiency, Progressive Hepatic Form

  • Gsd Type 4, Progressive Hepatic Form

  • Gsdiv, Progressive Hepatic Form

  • Glycogen Storage Disease Type 4, Progressive Hepatic Form

  • Glycogen Storage Disease Type Iv, Progressive Hepatic Form

  • Glycogenosis Due To Glycogen Branching Enzyme Deficiency, Progressive Hepatic Form

  • Glycogenosis Type 4, Progressive Hepatic Form

  • Glycogenosis Type Iv, Progressive Hepatic Form

  • Glycogen Storage Disease 4

  • Gsd-Iv

  • Storage Disease, Glycogen, Type Iv

Skin Benign Neoplasm
  • Neoplasm Of Skin By Site

  • Tumor Of The Skin

  • Skin Tumor

  • Benign Neoplasm Of Skin

  • Skin Neoplasms

Inflammatory Bowel Disease
  • Inflammatory Bowel Diseases

  • Bowel Disease, Inflammatory

Lymphoma, Mucosa-Associated Lymphoid Type
  • Malt Lymphoma

  • Gastric Lymphoma, Primary

  • Lymphoma, Malt, Somatic

  • Mucosa-Associated Lymphoid Tissue Lymphoma

  • Extranodal Marginal Zone B-Cell Lymphoma

  • MALTOMA

  • Marginal Zone B-Cell Lymphoma

  • Mucosa-Associated Lymphatic Tissue Lymphoma

  • Primary Gastric Lymphoma

  • Gastric Lymphoma

  • Familial Primary Gastric Lymphoma

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CYLD RGD RGD:1308346
Canis familiaris CYLD VGNC VGNC:50293
Macaca mulatta CYLD VGNC VGNC:71581
Bos taurus CYLD VGNC VGNC:49141
Mus musculus CYLD MGD MGI:1921506
Felis catus CYLD VGNC VGNC:61320
Others CYLD NCBI