HSPA12A - heat shock protein family A (Hsp70) member 12A Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 259217

About HSPA12A

Cytogenetic location: 10q25.3 Genomic coordinates (GRCh38): 10:116,671,192-116,850,747 (from NCBI)

This gene has 30 transcripts (splice variants), 204 orthologues and 4 paralogues. Broad expression in brain (RPKM 23.0), fat (RPKM 11.2) and 16 other tissues.

Summary

Predicted to enable ATP binding activity. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

HSPA12A Products (2)

mRNA Protein Name
NM_001330164.2 NP_001317093.1 heat shock 70 kDa protein 12A isoform 1
NM_025015.3 NP_079291.2 heat shock 70 kDa protein 12A isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
30679749 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heat shock 70 kDa protein 12A

  • heat shock 70kD protein 12A

HSPA12A Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
HSPA12A O43301 HSPA12B Homo sapiens Q96MM6
Anti Tag CoIP
33961781
Intra
HSPA12A O43301 HSPA12B Homo sapiens Q96MM6
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

HSPA12A Antibodies

Cat. No. Product Name Application Reactivity
HY-P83202 HspA12A Antibody (YA2947) WB, IHC-P, ICC/IF, IP Human, Mouse, Rat

Related Diseases

Diseases Alias
External Ear Disease

  • Diseases Of External Ear

  • Preauricular Cyst

  • Preauricular Sinus And Fistula

  • Preauricular Sinus Or Fistula
Otitis Externa

  • Swimmer'S Ear

  • Infective Otitis Externa

  • Acute Infective Otitis Externa
Leukoencephalopathy With Vanishing White Matter

  • Cree Leukoencephalopathy

  • Vanishing White Matter Disease

  • Ovarioleukodystrophy

  • Vanishing White Matter Leukodystrophy

  • Childhood Ataxia With Central Nervous System Hypomyelinization

  • Cach

  • Cach Syndrome

  • Myelinosis Centralis Diffusa

  • VWM

  • Cle

  • Childhood Ataxia With Central Nervous System Hypomyelination

  • Childhood Ataxia With Diffuse Central Nervous System Hypomyelination

  • Cach/Vwm

  • Cach/Vwm Syndrome

  • Childhood Ataxia With Central Nervous System Hypomyelination/Vanishing White Matter

  • Cree Leukoencehalopathy

  • Late Infantile Cach Syndrome

  • Juvenile Or Adult Cach Syndrome

  • Congenital Or Early Infantile Cach Syndrome

  • Leukodystrophy With Vanishing White Matter
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06420 HSPA12A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris HSPA12A VGNC VGNC:52995
Macaca mulatta HSPA12A VGNC VGNC:106059
Rattus norvegicus HSPA12A RGD RGD:1305531
Mus musculus HSPA12A MGD MGI:1920692
Bos taurus HSPA12A VGNC VGNC:55956
Others HSPA12A NCBI