Pde4c - phosphodiesterase 4C Gene

Also Known as Dpde1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 290646

Summary

Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity. Involved in negative regulation of Insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cilium. Predicted to be active in cytosol; nucleus; and perinuclear region of cytoplasm. Orthologous to human PDE4C (phosphodiesterase 4C). [provided by Alliance of Genome Resources, Apr 2022]

Pde4c Products (1)

mRNA Protein Name
NM_001276765.1 NP_001263694.1 cAMP-specific 3',5'-cyclic phosphodiesterase 4C

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: Inferred from mutant phenotype
18706893 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cAMP-specific 3',5'-cyclic phosphodiesterase 4C

  • cAMP-specific 35-cyclic phosphodiesterase 4C

  • phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-108047 MK-0873 Inhibitor 95.0% Phase 2

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-128358 MR-L2 Activator 98.63% Unkown
HY-119190 PF-06445974 Inhibitor 98.59% Unkown
HY-103050 ML-030 Inhibitor 99.28% Unkown
HY-100246 CI-1044 Inhibitor 98.02% Unkown
HY-131707 LEO 39652 Inhibitor 99.51% Unkown
HY-114052 NVP-ABE171 Inhibitor / Unkown
HY-179504 PDE4B-IN-6 Inhibitor / Unkown
HY-201403 LY2775240 Inhibitor / Unkown
HY-RS10224 PDE4C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-119799 UK-500001 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pde4c NCBI NCBI:5143