Pde4c - phosphodiesterase 4C Gene

Rattus norvegicus

Also known as Dpde1

Gene ID: 290646 | Gene type: protein coding

About Pde4c

Summary

Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity. Involved in negative regulation of Insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cilium. Predicted to be active in cytosol; nucleus; and perinuclear region of cytoplasm. Orthologous to human PDE4C (phosphodiesterase 4C). [provided by Alliance of Genome Resources, Apr 2022]

Pde4c Products(1)

mRNA	Protein	Name
NM_001276765.1	NP_001263694.1	cAMP-specific 3',5'-cyclic phosphodiesterase 4C

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus	IMP IMP: Inferred from mutant phenotype	18706893	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cAMP-specific 3',5'-cyclic phosphodiesterase 4C

cAMP-specific 35-cyclic phosphodiesterase 4C

phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila)

Related Agents

Pre-clinical Phase

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-128358	MR-L2	Activator	98.63%	Unkown
HY-119190	PF-06445974	Inhibitor	98.59%	Unkown
HY-103050	ML-030	Inhibitor	99.28%	Unkown
HY-100246	CI-1044	Inhibitor	98.02%	Unkown
HY-131707	LEO 39652	Inhibitor	99.51%	Unkown
HY-114052	NVP-ABE171	Inhibitor	/	Unkown
HY-179504	PDE4B-IN-6	Inhibitor	/	Unkown
HY-201403	LY2775240	Inhibitor	/	Unkown
HY-RS10224	PDE4C Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-119799	UK-500001	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Pde4c	NCBI	NCBI:5143

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