PEX5 - Pex5 peroxisomal biogenesis factor 5 Gene

Also Known as PTS1R; PTS1-BP

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 312703

Summary

Predicted to enable several functions, including peroxisome targeting sequence binding activity; protein C-terminus binding activity; and protein sequestering activity. Predicted to be involved in negative regulation of protein-containing complex assembly; protein targeting to peroxisome; and protein tetramerization. Predicted to act upstream of or within several processes, including fatty acid metabolic process; mitochondrial membrane organization; and nervous system development. Located in cytosol and peroxisomal membrane. Part of protein-containing complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to human PEX5 (peroxisomal biogenesis factor 5). [provided by Alliance of Genome Resources, Apr 2022]

PEX5 Products (1)

mRNA Protein Name
NM_001170584.1 NP_001164055.1 peroxisomal targeting signal 1 receptor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in peroxisomal membrane IDA
IDA: Inferred from direct assay
11397814 RGD
located in peroxisome IDA
IDA: Inferred from direct assay
11397814 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
11397814 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxisomal targeting signal 1 receptor

  • PTS1 receptor

  • peroxin-5

  • peroxisomal C-terminal targeting signal import receptor

  • peroxisomal targeting signal 1 receptor-like

  • peroxisome biogenesis factor 5

  • peroxisome receptor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-155530 PEX5-PEX14 PPI-IN-1 / Unkown
HY-155531 PEX5-PEX14 PPI-IN-2 / Unkown
HY-RS10351 PEX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10352 PEX5L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175517 PEX5-PEX14 PPI-IN-3 Inhibitor / Unkown
HY-182443 PEX5-PEX14 PPI-IN-4 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PEX5 NCBI NCBI:5830