2. Gene
  3. PEX5 - Pex5 peroxisomal biogenesis factor 5 Gene

PEX5 - Pex5 peroxisomal biogenesis factor 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as PTS1R; PTS1-BP

Gene ID: 312703 | Gene type: protein coding

About PEX5

Summary

Predicted to enable several functions, including peroxisome targeting sequence binding activity; protein C-terminus binding activity; and protein sequestering activity. Predicted to be involved in negative regulation of protein-containing complex assembly; protein targeting to peroxisome; and protein tetramerization. Predicted to act upstream of or within several processes, including fatty acid metabolic process; mitochondrial membrane organization; and nervous system development. Located in cytosol and peroxisomal membrane. Part of protein-containing complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to human PEX5 (peroxisomal biogenesis factor 5). [provided by Alliance of Genome Resources, Apr 2022]

PEX5 Products(1)

mRNA Protein Name
NM_001170584.1 NP_001164055.1 peroxisomal targeting signal 1 receptor
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in peroxisomal membrane IDA
IDA: Inferred from direct assay
11397814 RGD
located in peroxisome IDA
IDA: Inferred from direct assay
11397814 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
11397814 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxisomal targeting signal 1 receptor

PTS1 receptor

peroxin-5

peroxisomal C-terminal targeting signal import receptor

peroxisomal targeting signal 1 receptor-like

peroxisome biogenesis factor 5

peroxisome receptor 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-155530 PEX5-PEX14 PPI-IN-1 / Unkown
HY-155531 PEX5-PEX14 PPI-IN-2 / Unkown
HY-RS10351 PEX5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10352 PEX5L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175517 PEX5-PEX14 PPI-IN-3 Inhibitor / Unkown
HY-182443 PEX5-PEX14 PPI-IN-4 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PEX5 NCBI NCBI:5830