PEX5-PEX14 PPI-IN-1
PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 PPI inhibitor. PEX5-PEX14 PPI-IN-1 disrupts the PEX5-TbPEX14 PPI with a Ki of 53 μM. PEX5-PEX14 PPI-IN-1 inhibits the bloodstream form of T. b. brucei (EC50: 5 μM).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3052256-26-2
- 分子式: C26H28N4O3
- 分子量:444.53
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | EC50 |
21 μM
Compound: 8
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 66 hrs by resazurin staining based analysis
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 66 hrs by resazurin staining based analysis
|
[PMID: 37406382] |
化学情報
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CAS 番号 3052256-26-2
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分子量 444.53
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分子式 C26H28N4O3
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SMILES
O=C(OC)[C@@H](N1C([C@H](CC2=CNC3=C2C=CC=C3)NCCC1)=O)CC4=CNC5=C4C=CC=C5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)