3052256-26-2

PEX5-PEX14 PPI-IN-1 Chemical Structure
3052256-26-2

Chemical Structure

PEX5-PEX14 PPI-IN-1

  • CAS No.: 3052256-26-2
  • Formula:C26H28N4O3
  • Molecular Weight:444.53

InChIKey: GKTCEZLBMOVKOI-ZEQRLZLVSA-N

SMILES: O=C(OC)[C@@H](N1C([C@H](CC2=CNC3=C2C=CC=C3)NCCC1)=O)CC4=CNC5=C4C=CC=C5

Biological Activity: PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 PPI inhibitor. PEX5-PEX14 PPI-IN-1 disrupts the PEX5-TbPEX14 PPI with a Ki of 53 μM. PEX5-PEX14 PPI-IN-1 inhibits the bloodstream form of T. b. brucei (EC50: 5 μM)[1].

Cat. No. Product Name Purity Description Pricing
HY-155530
PEX5-PEX14 PPI-IN-1 PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 PPI inhibitor. PEX5-PEX14 PPI-IN-1 disrupts the PEX5-TbPEX14 PPI with a Ki of 53 μM. PEX5-PEX14 PPI-IN-1 inhibits the bloodstream form of T. b. brucei (EC50: 5 μM).
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