PEX5-PEX14 PPI-IN-2
PEX5-PEX14 PPI-IN-2 (compound 12) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor. PEX5-PEX14 PPI-IN-2 inhibits PEX14-PEX5 PPI with EC50 values of 5 and 17 µM in T. b. brucei and HepG2 cells, respectively. PEX5-PEX14 PPI-IN-2 can be used in the research of diseases related to trypanosome infection.
For research use only. We do not sell to patients.
- CAS No.: 3052256-03-5
- Formula: C25H26N4O3
- Molecular Weight:430.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | EC50 |
17 μM
Compound: 12
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 66 hrs by resazurin staining based analysis
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 66 hrs by resazurin staining based analysis
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[PMID: 37406382] |
Chemical Information
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CAS No. 3052256-03-5
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Molecular Weight 430.50
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Formula C25H26N4O3
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SMILES
O=C(OC)[C@@H](N1C[C@H](CC2=CNC3=C2C=CC=C3)NC(C1)=O)CC4=CNC5=C4C=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PEX5-PEX14 PPI-IN-2 Related Classifications
HY-155531 Related Classifications
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