ANKRD37 - ankyrin repeat domain 37 Gene

Also Known as Lrp2bp

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 353322

About ANKRD37

Cytogenetic location: 4q35.1 Genomic coordinates (GRCh38): 4:185,396,841-185,400,723 (from NCBI)

This gene has 6 transcripts (splice variants), 140 orthologues and 1 paralogue. Ubiquitous expression in esophagus (RPKM 19.3), prostate (RPKM 17.2) and 25 other tissues.

Summary

Located in cytosol; mitochondrion; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ANKRD37 Products (1)

mRNA	Protein	Name
NM_181726.4	NP_859077.1	ankyrin repeat domain-containing protein 37

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ANKRD37 Protein Structure

Ank_2

0
100
158 a.a.

Protein Preferred Names	Protein Names
ankyrin repeat domain-containing protein 37	low density lipoprotein receptor-related protein binding protein

ANKRD37 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	ANKRD37	Q7Z713	HIF1AN	Homo sapiens	Q9NWT6	Y2H Prey Pooling	32296183
Intra	ANKRD37	Q7Z713	HIF1AN	Homo sapiens	Q9NWT6	Validated Y2H	32296183
Intra	ANKRD37	Q7Z713	HIF1AN	Homo sapiens	Q9NWT6	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Donnai-Barrow Syndrome	Faciooculoacousticorenal Syndrome Dbs/Foar Syndrome Foar Syndrome Diaphragmatic Hernia-Exomphalos-Hypertelorism Syndrome Facio-Oculo-Acoustico-Renal Syndrome Diaphragmatic Hernia, Exomphalos, Absent Corpus Callosum, Hypertelorism, Myopia, Sensorineural Deafness, And Proteinuria Diaphragmatic Hernia-Hypertelorism-Myopia-Deafness Syndrome Holmes-Schepens Syndrome Syndrome Of Ocular And Facial Anomalies, Telecanthus And Deafness DBS Diaphragmatic Hernia Exomphalos Absent Corpus Callosum Hypertelorism Myopia Sensorineural Deafness And Proteinuria Diaphragmatic Hernia-Exomphalos-Corpus Callosum Agenesis Diaphragmatic Hernia-Hypertelorism-Myopia-Hearing Loss Syndrome Syndrome Of Ocular And Facial Anomalies, Telecanthus And Hearing Loss Donnai Barrow Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00727	ANKRD37 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ANKRD37	VGNC	VGNC:59811
Macaca mulatta	ANKRD37	VGNC	VGNC:106544
Mus musculus	ANKRD37	MGD	MGI:3603344
Canis familiaris	ANKRD37	VGNC	VGNC:37901
Bos taurus	ANKRD37	VGNC	VGNC:25928
Rattus norvegicus	ANKRD37	RGD	RGD:1565715
Others	ANKRD37	NCBI