2. Gene
  3. MEIS2 - Meis homeobox 2 Gene

MEIS2 - Meis homeobox 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MRG1; CPCMR; HsT18361

Gene ID: 4212 | Gene type: protein coding

About MEIS2

Cytogenetic location: 15q14 Genomic coordinates (GRCh38): 15:36,889,204-37,101,311 (from NCBI)

This gene has 38 transcripts (splice variants), 289 orthologues, 12 paralogues and is associated with 3 phenotypes. Ubiquitous expression in endometrium (RPKM 12.8), prostate (RPKM 12.0) and 24 other tissues.

Summary

This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

MEIS2 Products(8)

mRNA Protein Name
NM_001220482.2 NP_001207411.1 homeobox protein Meis2 isoform d
NM_002399.4 NP_002390.1 homeobox protein Meis2 isoform f
NM_170674.5 NP_733774.1 homeobox protein Meis2 isoform b
NM_170675.5 NP_733775.1 homeobox protein Meis2 isoform c
NM_170676.5 NP_733776.1 homeobox protein Meis2 isoform d
NM_170677.5 NP_733777.1 homeobox protein Meis2 isoform a
NM_172315.3 NP_758526.1 homeobox protein Meis2 isoform g
NM_172316.3 NP_758527.1 homeobox protein Meis2 isoform h

MEIS2 Protein Structure

Homeobox_KN

Homeobox_KN: Homeobox KN domain (294 - 333)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 477 a.a.
Protein Preferred Names Protein Names

homeobox protein Meis2

Meis homolog 2

Related Diseases

Diseases Alias
Cleft Palate, Cardiac Defects, And Mental Retardation

Cardiac Malformation, Cleft Lip/Palate, Microcephaly, And Digital Anomalies

CPCMR

Cleft Palate, Cardiac Defects, And Intellectual Disabillity

Cleft Palate, Cardiac Defects, And Intellectual Disability

Cardiac Malformation, Cleft Lip-Palate, Microcephaly And Digital Anomalies
Chromosome 15q14 Deletion Syndrome

15q14 Microdeletion Syndrome

Del(15)(Q14)

Monosomy 15q14
Cleft Palate, Cardiac Defects, And Intellectual Disability
Congenital Anomalies Of Kidney And Urinary Tract Syndrome With Or Without Hearing Loss, Abnormal Ears, Or Developmental Delay

CAKUTHED

Doid:0112359

Anomalies, Congenital, Kidney And Urinary Tract Syndrome With/Without Hearing Loss, Abnormal Ears, Or Developmental Delay
Epilepsy, Familial Temporal Lobe, 4

ETL4

Epilepsy, Occipitotemporal Lobe, And Migraine With Aura

Epolm

Familial Temporal Lobe Epilepsy 4

Occipitotemporal Lobe Epilepsy And Migraine With Aura
Anemia, Congenital Dyserythropoietic, Type Ib

CDAN1B

Congenital Dyserythropoietic Anemia Type Ib

Cda, Type Ib

Congenital Dyserythropoietic Anemia Type Type 1b

Dyserythropoietic Anemia, Congenital, Type Ib

Anemia, Congenital Dyserythropoietic, 1b

Cda Ib

Anemia, Dyserythropoietic, Congenital

Anemia, Dyserythropoietic, Congenital, Type Ib
Breast Lipoma

Lipoma Of Breast
Peters-Plus Syndrome

Krause-Kivlin Syndrome

Peters Plus Syndrome

Peters Anomaly

Irido-Corneo-Trabecular Dysgenesis

PTRPLS

Peters Anomaly With Short-Limb Dwarfism

Peters Anomaly-Short Limb Dwarfism Syndrome

Peters Anomaly With Short Limb Dwarfism

Peters Congenital Glaucoma

Krause-Van Schooneveld-Kivlin Syndrome

Peters' Plus Syndrome

Peters'-Plus Syndrome

Anomaly Peters
Axenfeld-Rieger Syndrome

Axenfeld Syndrome

Rieger Syndrome

Rieger Anomaly

Axenfeld Anomaly

Anomaly, Rieger'S

Hagedoom Syndrome

Rgs - Rieger Syndrome

Rieger'S Anomaly

Goniodysgenesis Hypodontia

Iridogoniodysgenesis With Somatic Anomalies

Ars

Axenfeld And Rieger Anomaly

Axra

Axrs

Rieger Eye Malformation Sequence
Aniridia 1

Aniridia

Congenital Aniridia

AN1

An

Cataract With Late-Onset Corneal Dystrophy

Aplasia Of Iris

Absent Iris

Irideremia

Aniridia Ii, Formerly

An2, Formerly

An2

Aniridia Type Ii

Aniridia, Type 1

An-1

Absence Of Iris

Agenesis Of Iris

Congenital Absence Of Iris

Hereditary Aniridia

Sporadic Aniridia
Orofacial Cleft

Cleft, Orofacial
Cone-Rod Dystrophy 2

Cone-Rod Dystrophy

CORD2

Cone-Rod Retinal Dystrophy

Rcrd2

Cone-Rod Retinal Dystrophy 2

Crd2

Cord

Crd

Retinal Cone-Rod Dystrophy

Cone-Rod Retinal Dystrophy-2

Retinal Cone-Rod Dystrophy 2

Tapetoretinal Degeneration

Cone-Rod Degeneration

Cone Rod Dystrophy

Dystrophy, Cone-Rod

Dystrophy, Cone-Rod, Type 2

Retinitis Pigmentosa

Retinitis Pigmentosa 2

Progressive Cone-Rod Dystrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08326 MEIS2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MEIS2 RGD RGD:1305198
Mus musculus MEIS2 MGD MGI:108564
Macaca mulatta MEIS2 VGNC VGNC:74702
Bos taurus MEIS2 VGNC VGNC:31382
Felis catus MEIS2 VGNC VGNC:80914
Canis familiaris MEIS2 VGNC VGNC:43154