INSR - insulin receptor Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 484990

About INSR

Primary_assembly 20: 52,551,139-52,683,109 reverse strand.ROS_Cfam_1.0:CM025119.1

This gene has 3 transcripts (splice variants), 289 orthologues and 54 paralogues.

INSR Products (4)

mRNA Protein Name
XM_038428733.1 XP_038284661.1 insulin receptor isoform X4
XM_038428731.1 XP_038284659.1 insulin receptor isoform X2
XM_038428732.1 XP_038284660.1 insulin receptor isoform X3
XM_038428729.1 XP_038284657.1 insulin receptor isoform X1

INSR Protein Structure

Recep_L_domain

Recep_L_domain: pfam01030 (14 - 126)

Furin-like

Furin-like: pfam00757 (141 - 299)

Recep_L_domain

Recep_L_domain: pfam01030 (321 - 434)

FN3

FN3: cd00063 (584 - 627)

FN3

FN3: cd00063 (828 - 905)

Insulin_TMD

Insulin_TMD: pfam17870 (901 - 948)

PTKc_InsR

PTKc_InsR: cd05061 (977 - 1264)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1344 a.a.
Protein Preferred Names Protein Names

LOW QUALITY PROTEIN: insulin receptor

insulin receptor

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15656 Ceritinib Inhibitor 99.95% Yes
HY-15656A Ceritinib dihydrochloride Inhibitor 99.90% Yes
HY-15656AR Ceritinib dihydrochloride (Standard) Inhibitor / Unkown
HY-15656R Ceritinib (Standard) Inhibitor 99.72% Unkown

Clinical Phase

Bioactive MoleculesInhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P990712 Ersodetug Inhibitor 99.33% Phase 3
HY-P991037 Verenafusp alfa / Phase 1

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-50866 NVP-AEW541 99.92% Unkown
HY-13203 NVP-TAE 226 99.77% Unkown
HY-10252 NVP-ADW742 99.30% Unkown
HY-15656S Ceritinib-d7 Inhibitor 98.00% Unkown
HY-RS06847 Insr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-50866B NVP-AEW541 dihydrochloride / Unkown
HY-10252A cis-NVP-ADW742 Inhibitor / Unkown
HY-108230 ALK-IN-12 Inhibitor / Unkown
HY-15656B Ceritinib mesylate Inhibitor / Unkown
HY-169066 INSR agonist 1 Agonist / Unkown
HY-180972 PROTAC EML4-ALK Degrader-2 Inhibitor / Unkown
HY-183292 SH-1092 Inhibitor / Unkown
HY-E70730 INSR Recombinant Human Active Protein Kinase / Unkown
HY-RS06846 INSR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06848 Insr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991290 IRAB-B Antagonist 98.30% Unkown
HY-P991291 XOMA 129 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens INSR NCBI NCBI:3643
Felis catus INSR NCBI NCBI:100127108
Canis lupus familiaris INSR NCBI