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51088

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By Targets:	5-HT Receptor (5) Adenosine Receptor (1) Adrenergic Receptor (1) Antibiotic (1) Aurora Kinase (2) Autophagy (1) Bacterial (1) BCRP (2) DNA/RNA Synthesis (1) Dopamine β-hydroxylase (2) Fungal (1) Ligands for Target Protein for PROTAC (1) MicroRNA (16) P-glycoprotein (2) Parasite (1) Prostaglandin Receptor (3) Reference Standards (4)
By Research Areas:	Cancer (21) Cardiovascular Disease (2) Infection (3) Inflammation/Immunology (2) Metabolic Disease (4) Neurological Disease (8)
Click Chemistry:	Alkynes (1)
Oligonucleotides:	miRNA mimics (4) miRNA agomirs (4) miRNA antagomirs (4) MicroRNAs (16) miRNA inhibitors (4)

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Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-112258

IMP-1088 Maximum Cited Publications 8 Publications Verification	DNA/RNA Synthesis	Infection
IMP-1088 is a potent human N-myristoyltransferases NMT1 and NMT2 dual inhibitor with IC₅₀s of <1 nM for HsNMT1 and HsNMT2. IMP-1088 has a K_d of <210 pM for HsNMT1. IMP-1088 efficiently blocks rhinovirus replication by blocking rhinovirus virus-encoded protein (VP0) N-myristoylation. IMP-1088 protects host cells from the cytotoxic effects of viral infection .

HY-13252

MK-5108 5+ Cited Publications VX-689	Aurora Kinase Autophagy	Cancer
MK-5108 is a highly potent and specific inhibitor of Aurora A kinase with an IC₅₀ value of 0.064 nM.

HY-10457

Velusetrag TD-5108	5-HT Receptor	Neurological Disease Metabolic Disease
Velusetrag (TD-5108) is an orally active, potent and selective agonist of serotonin 5-HT₄ receptor (5-HT4R), with a pK_i of 7.7. Velusetrag exhibits no affinity (K_i>10 μM) for 5-HT_2A and 5-HT_2B receptors. Velusetrag can be used for the research of gastrointestinal diseases and Parkinson's disease .

HY-106004

Zamicastat BIA 5-1058	Dopamine β-hydroxylase P-glycoprotein BCRP	Cardiovascular Disease Cancer
Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC₅₀ values of 73.8 μM and 17.0 μM, respectively . Zamicastat reduces high blood pressure .

HY-108563

SC 51089	Prostaglandin Receptor	Neurological Disease
SC 51089 is a selective antagonist of prostaglandin E₂ EP1 receptor, with K_is of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively. SC 51089 exhibits neuroprotective activity .

HY-108563A

*SC 51089* free base** 1 Publications Verification	Prostaglandin Receptor	Neurological Disease
SC 51089 free base is a selective antagonist of prostaglandin E₂ EP1 receptor, with K_is of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively. SC 51089 free base exhibits neuroprotective activity .

HY-10457A

Velusetrag hydrochloride TD-5108 hydrochloride	5-HT Receptor	Neurological Disease Metabolic Disease
Velusetrag (TD-5108) hydrochloride is an orally active, potent and selective agonist of serotonin 5-HT₄ receptor (5-HT₄R), with a pK_i of 7.7. Velusetrag hydrochloride exhibits no affinity (K_i>10 μM) for 5-HT_2A and 5-HT_2B receptors. Velusetrag hydrochloride can be used for the research of gastrointestinal diseases and Parkinson's disease .

HY-118992

Aurodox X 5108; Goldinomycin	Antibiotic Bacterial	Infection
Aurodox (X 5108) is an antibiotic obtained from a streptomyces variant, Aurodox can against a number of gram-positive bacteria. Aurodox shows a very low toxicity in mice and promoted poultry growth .

HY-175827

*MK-5108-NH-PEG2-alkyne*	Aurora Kinase Ligands for Target Protein for PROTAC	Cancer
MK-5108-NH-PEG2-alkyne is a Aurora kinase A (AURKA) inhibitor. MK-5108-NH-PEG2-alkyne can be used for synthesis of PROTAC AURKA degrader 1 (HY-175830) .

HY-I0903

SCH 51048	Fungal	Others
SCH 51048 is a compound that can produce active metabolites, and its active metabolites have antifungal activity. Through metabolic studies and activity screening of the compound, metabolites and compounds with better activity were discovered.

HY-12706

Spiroxatrine R 5188	Adrenergic Receptor 5-HT Receptor	Neurological Disease Inflammation/Immunology
Spiroxatrine (R 5188) is a selective, dual antagonist of 5-HT1α and α2-adrenergic, with the K_i values of 3.94, 224000, 118.5 nM for 5-HT1α, 5-HT1β and 5-HT2, respectively. Spiroxatrine (R 5188) has a sedative effect .

HY-162778

FM-1088	Parasite	Infection
FM-1088 is an insecticide. FM-1088 can be used in research related to crop disease and insect pest control .

HY-R03254

*mmu-miR-5108* mimic**	MicroRNA	Cancer
mmu-miR-5108 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

mmu-miR-5108 mimic mmu-miR-5108 mimic

HY-R01523

*hsa-miR-5088-3p mimic*	MicroRNA	Cancer
hsa-miR-5088-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5088-3p mimic hsa-miR-5088-3p mimic

HY-R01524

*hsa-miR-5088-5p mimic*	MicroRNA	Cancer
hsa-miR-5088-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5088-5p mimic hsa-miR-5088-5p mimic

HY-108563AR

*SC 51089* free base (Standard)**	Reference Standards Prostaglandin Receptor	Neurological Disease
SC 51089 free base (Standard) is the analytical standard of SC 51089 (free base) (HY-108563A). This product is intended for research and analytical applications. SC 51089 free base is a selective antagonist of prostaglandin E2 EP1 receptor, with K_is of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively. SC 51089 free base exhibits neuroprotective activity .

HY-183599

MK-1088	Adenosine Receptor	Cancer
MK-1088 is an orally active A_2A/A_2B adenosine receptor antagonist with human A_2A K_i of 0.31 nM, human A_2B K_i 5.3 nM. MK-1088 blocks receptor downstream signaling, inhibits CREB phosphorylation and reverses adenosine-mediated immunosuppression. MK-1088 restores TNF−α release and enhances tumor immune surveillance. MK-1088 can be used for the research of cancer^[1].

HY-R01562

*hsa-miR-5188* mimic**	MicroRNA	Cancer
hsa-miR-5188 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5188 mimic hsa-miR-5188 mimic

HY-RI01562

*hsa-miR-5188* inhibitor**	MicroRNA	Cancer
hsa-miR-5188 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5188 inhibitor hsa-miR-5188 inhibitor

HY-RI03254A

*mmu-miR-5108* antagomir**	MicroRNA	Cancer
mmu-miR-5108 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5108 antagomir mmu-miR-5108 antagomir

HY-RI01562A

*hsa-miR-5188* antagomir**	MicroRNA	Cancer
hsa-miR-5188 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5188 antagomir hsa-miR-5188 antagomir

HY-R01562A

*hsa-miR-5188* agomir**	MicroRNA	Cancer
hsa-miR-5188 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5188 agomir hsa-miR-5188 agomir

HY-RI03254

*mmu-miR-5108* inhibitor**	MicroRNA	Cancer
mmu-miR-5108 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

mmu-miR-5108 inhibitor mmu-miR-5108 inhibitor

HY-R03254A

*mmu-miR-5108* agomir**	MicroRNA	Cancer
mmu-miR-5108 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

mmu-miR-5108 agomir mmu-miR-5108 agomir

HY-106004R

Zamicastat (Standard) BIA 5-1058 (Standard)	Reference Standards Dopamine β-hydroxylase P-glycoprotein BCRP	Cardiovascular Disease Cancer
Zamicastat (Standard) is the analytical standard of Zamicastat (HY-106004). This product is intended for research and analytical applications. Zamicastat (BIA 5-1058) is a dopamine β-hydroxylase (DBH) inhibitor and can cross the blood-brain barrier (BBB) to cause central as well as peripheral effects. Zamicastat is also a concentration-dependent dual P-gp and BCRP inhibitor with IC₅₀ values of 73.8 μM and 17.0 μM, respectively . Zamicastat reduces high blood pressure .

HY-10457R

Velusetrag (Standard) TD-5108 (Standard)	Reference Standards 5-HT Receptor	Neurological Disease Metabolic Disease
Velusetrag (Standard) is the analytical standard of Velusetrag (HY-10457). This product is intended for research and analytical applications. Velusetrag (TD-5108) is an orally active, potent and selective agonist of serotonin 5-HT4 receptor (5-HT4R), with a pK_i of 7.7. Velusetrag exhibits no affinity (Ki>10 μM) for 5-HT2A and 5-HT2B receptors. Velusetrag can be used for the research of gastrointestinal diseases and Parkinson's disease .

HY-10457AR

Velusetrag hydrochloride (Standard) TD-5108 hydrochloride (Standard)	Reference Standards 5-HT Receptor	Neurological Disease Metabolic Disease
Velusetrag hydrochloride (Standard) is the analytical standard of Velusetrag hydrochloride (HY-10457A). This product is intended for research and analytical applications. Velusetrag (TD-5108) hydrochloride is an orally active, potent and selective agonist of serotonin 5-HT4 receptor (5-HT4R), with a pK_i of 7.7. Velusetrag hydrochloride exhibits no affinity (Ki>10 μM) for 5-HT2A and 5-HT2B receptors. Velusetrag hydrochloride can be used for the research of gastrointestinal diseases and Parkinson's disease .

HY-R01523A

*hsa-miR-5088-3p agomir*	MicroRNA	Cancer
hsa-miR-5088-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5088-3p agomir hsa-miR-5088-3p agomir

HY-RI01523

*hsa-miR-5088-3p inhibitor*	MicroRNA	Cancer
hsa-miR-5088-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5088-3p inhibitor hsa-miR-5088-3p inhibitor

HY-RI01524A

*hsa-miR-5088-5p antagomir*	MicroRNA	Cancer
hsa-miR-5088-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5088-5p antagomir hsa-miR-5088-5p antagomir

HY-RI01524

*hsa-miR-5088-5p inhibitor*	MicroRNA	Cancer
hsa-miR-5088-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5088-5p inhibitor hsa-miR-5088-5p inhibitor

HY-RI01523A

*hsa-miR-5088-3p antagomir*	MicroRNA	Cancer
hsa-miR-5088-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5088-3p antagomir hsa-miR-5088-3p antagomir

HY-R01524A

*hsa-miR-5088-5p agomir*	MicroRNA	Cancer
hsa-miR-5088-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5088-5p agomir hsa-miR-5088-5p agomir

Cat. No.	Product Name	Target	Research Area	Image

HY-P990641

NTX-1088	Inhibitory Antibodies	Inflammation/Immunology
NTX-1088 is a CHO-expressed humanized antibody that targets PVR/CD155. NTX-1088 contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145.86 kDa. The isotype control for NTX-1088 can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

Aurodox X 5108; Goldinomycin	Infection Microorganisms Classification of Application Fields Antibiotics Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Aurodox (X 5108) is an antibiotic obtained from a streptomyces variant, Aurodox can against a number of gram-positive bacteria. Aurodox shows a very low toxicity in mice and promoted poultry growth .

Host:	Mouse (4) Rabbit (1)
Reactivity:	Human (5) Bovine (1) Rat (4) Mouse (2) Chicken (1) Pig (1)
Application:	IHC-P (2) ICC/IF (2) IF-Tissue (1) IP (2) IHC-F (1) WB (5)
Isotype:	IgG (1) IgG1 (2)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85416

	AKT1 Antibody (YA5108) AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha	WB	Human, Mouse, Rat, Bovine, Chicken, Pig
	AKT1 Antibody (YA5108) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to AKT1.

HY-P85396

	Trk-A Antibody (YA5088) NTRK1; MTC; TRK; TRKA; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A;	WB, IHC-P, IHC-F, IF-Tissue, ICC/IF	Mouse, Rat, Human
	Trk-A Antibody (YA5088) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Trk-A.

HY-P81343

	MAP2K6 Antibody (YA1088) MAP2K6; MEK6; MKK6; PRKMK6; SKK3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPKK 6; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3	WB, IP	Human, Rat
	MAP2K6 Antibody (YA1088) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MAP2K6.

HY-P81343A

	MAP2K6 Antibody (YA1088)(PBS only) MAP2K6; MEK6; MKK6; PRKMK6; SKK3; Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPKK 6; MAPK/ERK kinase 6; MEK 6; Stress-activated protein kinase kinase 3; SAPK kinase 3; SAPKK-3; SAPKK3	WB, IP	Human, Rat
	MAP2K6 Antibody (YA1088) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MAP2K6.

HY-P85496

	PRMT6 Antibody (YA5188) ANM6_HUMAN; Chromobox protein homolog 7; FLJ10559; FLJ51477; Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 6; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6; HMT1 hnRNP methyltransferase like 6.; HRMT1L6; OTTHUMP00000012633; PRMT 6; prmt6; Protein arginine methyltransferase 6; Protein arginine N methyltransferase 6; Protein arginine N-methyltransferase 6.	WB, IHC-P, ICC/IF	Human
	PRMT6 Antibody (YA5188) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PRMT6.

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Cat. No.	Product Name		Classification

HY-175827

*MK-5108-NH-PEG2-alkyne*		Alkynes
MK-5108-NH-PEG2-alkyne is a Aurora kinase A (AURKA) inhibitor. MK-5108-NH-PEG2-alkyne can be used for synthesis of PROTAC AURKA degrader 1 (HY-175830) .

Cat. No.	Product Name		Classification

HY-R03254

*mmu-miR-5108* mimic**		MicroRNAs miRNA mimics
mmu-miR-5108 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01523

*hsa-miR-5088-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-5088-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01524

*hsa-miR-5088-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-5088-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01562

*hsa-miR-5188* mimic**		MicroRNAs miRNA mimics
hsa-miR-5188 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI01562

*hsa-miR-5188* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-5188 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03254A

*mmu-miR-5108* antagomir**		MicroRNAs miRNA antagomirs
mmu-miR-5108 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01562A

*hsa-miR-5188* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-5188 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01562A

*hsa-miR-5188* agomir**		MicroRNAs miRNA agomirs
hsa-miR-5188 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03254

*mmu-miR-5108* inhibitor**		MicroRNAs miRNA inhibitors
mmu-miR-5108 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R03254A

*mmu-miR-5108* agomir**		MicroRNAs miRNA agomirs
mmu-miR-5108 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01523A

*hsa-miR-5088-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5088-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01523

*hsa-miR-5088-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5088-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01524A

*hsa-miR-5088-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5088-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01524

*hsa-miR-5088-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5088-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01523A

*hsa-miR-5088-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5088-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01524A

*hsa-miR-5088-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5088-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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51088

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