PLK4 - polo like kinase 4 Gene

Also Known as PLK-4

Species: Bos taurus

Gene Type: protein coding
Gene ID: 514405

About PLK4

Primary_assembly 17: 29,774,988-29,792,009 reverse strand.ARS-UCD1.2:CM008184.2

This gene has 1 transcript (splice variant), 209 orthologues and 4 paralogues.

PLK4 Products (1)

mRNA Protein Name
NM_001083427.2 NP_001076896.1 serine/threonine-protein kinase PLK4

PLK4 Protein Structure

STKc_PLK4

STKc_PLK4: cd14186 (9 - 264)

Plk4_PB1

Plk4_PB1: pfam18190 (513 - 619)

Plk4_PB2

Plk4_PB2: pfam18409 (621 - 729)

POLO_box_Plk4_3

POLO_box_Plk4_3: cd13116 (806 - 885)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 893 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase PLK4

  • serine/threonine-protein kinase Sak

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-149324 SP27 Degrader 98.87% Phase 4
HY-12300 Ocifisertib Inhibitor 99.78% Phase 2
HY-12300B Ocifisertib fumarate Inhibitor 98.69% Phase 2
HY-172737 RP-1664 Inhibitor 98.77% Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18682 Centrinone Inhibitor 98.30% Unkown
HY-100789 ON1231320 Inhibitor 99.90% Unkown
HY-18683 Centrinone-B Inhibitor 98.65% Unkown
HY-128493 PLK4-IN-4 Inhibitor 99.69% Unkown
HY-132135 (1E)-CFI-400437 dihydrochloride Inhibitor 98.08% Unkown
HY-149912 CZS-241 Inhibitor / Unkown
HY-12300A Ocifisertib hydrochloride Inhibitor 98.29% Unkown
HY-134775A PLK4-IN-3 Inhibitor / Unkown
HY-179149 PLK4-IN-6 Inhibitor / Unkown
HY-176734 CZL-S092 Inhibitor / Unkown
HY-187506 ZSL-M028 Inhibitor / Unkown
HY-115589 YLT-11 Inhibitor / Unkown
HY-180111 PLK4-IN-7 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PLK4 NCBI NCBI:10733