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55684

" within the MedChemExpress (MCE) catalog. Here are the results you might be looking for.

By Targets:	Acetyl-CoA Carboxylase (1) COX (1) Cytochrome P450 (1) EBV (1) Leukotriene Receptor (1) Lipoxygenase (1) MicroRNA (12) mTOR (3) Parasite (1) Phospholipase (1) PI3K (3) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (17) Infection (2) Inflammation/Immunology (2)
Oligonucleotides:	miRNA mimics (3) miRNA antagomirs (3) miRNA agomirs (3) MicroRNAs (12) miRNA inhibitors (3)

Inhibitors & Agonists

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-156628

Opevesostat MK-5684; ODM-208	Cytochrome P450	Cancer
Opevesostat (MK-5684; ODM-208) is an orally active and selective CYP11A1 inhibitor. Opevesostat has the potential for the research of metastatic castration-resistant prostate cancer (mCRPC) .

HY-16585

VS-5584 5 Publications Verification SB2343	PI3K mTOR	Cancer
VS-5584 is a pan-PI3K/mTOR kinase inhibitor with IC₅₀s of 16 nM, 68 nM, 42 nM, 25 nM, and 37 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively. VS-5584 simultaneously blocks mTORC2 as well as mTORC1.

HY-105070A

Eritoran tetrasodium E5564	EBV Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Eritoran tetrasodium (E5564) is a Toll-like receptor 4 (TLR4) antagonist. Eritoran tetrasodium protects mice against lethal influenza virus infection, such as Ebola virus (EBOV), Marburg virus (MARV). Eritoran tetrasodium decreases the level of granulocytosis, may alleviate the severity of the "cytokine storm". Eritoran tetrasodium inhibits pathogenesis of filovirus infection. Eritoran tetrasodium has anti-inflammatory activity .

HY-19910

Acoziborole 3 Publications Verification SCYX-7158; AN5568	Parasite	Infection
Acoziborole (SCYX-7158) is an effective, safe and orally active antiprotozoal agent for the research of human african trypanosomiasis (HAT). In the *T. b. brucei* S427 strain, the MIC value for SCYX-7158 is 0.6 μg/mL .

HY-161116

AD-5584	Acetyl-CoA Carboxylase	Cancer
AD-5584 is an ACSS2 inhibitor with blood-brain permeability. AD-5584 can significantly reduce lipid storage, reduce colony formation, and increase cell death. AD-5584 has antitumor activity .

HY-114873

LY256548 LY25684	Phospholipase COX Lipoxygenase Leukotriene Receptor	Inflammation/Immunology
LY256548 (LY25648) is an orally available anti-ischemic and anti-inflammatory compound with central nervous system activity. LY256548 is an inhibitor of phospholipase A2, 5-lipoxygenase (5-LOX), and COX, and inhibits A23187 (HY-N6687)-stimulated leukotriene B4 production. LY256548 inhibits bone damage and paw swelling in the rat Freund's complete adjuvant-induced arthritis (FCA) model .

HY-R01763

*hsa-miR-5684* mimic**	MicroRNA	Cancer
hsa-miR-5684 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5684 mimic hsa-miR-5684 mimic

HY-101776A

*Desmethyl-VS-5584* hydrochloride** Desmethyl-SB2343 hydrochloride	PI3K mTOR	Cancer
Desmethyl-VS-5584 hydrochloride is a dimethyl analog of VS-5584, a potent and selective mTOR/< with a pyridine[2,3-d]pyrimidine structure. b>PI3KDual inhibitor .

HY-RI01734A

*hsa-miR-5584-3p antagomir*	MicroRNA	Cancer
hsa-miR-5584-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5584-3p antagomir hsa-miR-5584-3p antagomir

HY-R01734

*hsa-miR-5584-3p mimic*	MicroRNA	Cancer
hsa-miR-5584-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5584-3p mimic hsa-miR-5584-3p mimic

HY-101776

Desmethyl-VS-5584 Desmethyl-SB2343	mTOR PI3K	Cancer
Desmethyl-VS-5584 is a dimethyl analog of VS-5584 which is an potent and selective mTOR/PI3K dual inhibitor with pyrido [2,3-d] pyrimidine structure .

HY-R01735

*hsa-miR-5584-5p mimic*	MicroRNA	Cancer
hsa-miR-5584-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-5584-5p mimic hsa-miR-5584-5p mimic

HY-R01763A

*hsa-miR-5684* agomir**	MicroRNA	Cancer
hsa-miR-5684 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5684 agomir hsa-miR-5684 agomir

HY-RI01763A

*hsa-miR-5684* antagomir**	MicroRNA	Cancer
hsa-miR-5684 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5684 antagomir hsa-miR-5684 antagomir

HY-RI01763

*hsa-miR-5684* inhibitor**	MicroRNA	Cancer
hsa-miR-5684 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5684 inhibitor hsa-miR-5684 inhibitor

HY-R01734A

*hsa-miR-5584-3p agomir*	MicroRNA	Cancer
hsa-miR-5584-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5584-3p agomir hsa-miR-5584-3p agomir

HY-RI01735

*hsa-miR-5584-5p inhibitor*	MicroRNA	Cancer
hsa-miR-5584-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5584-5p inhibitor hsa-miR-5584-5p inhibitor

HY-R01735A

*hsa-miR-5584-5p agomir*	MicroRNA	Cancer
hsa-miR-5584-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5584-5p agomir hsa-miR-5584-5p agomir

HY-RI01735A

*hsa-miR-5584-5p antagomir*	MicroRNA	Cancer
hsa-miR-5584-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-5584-5p antagomir hsa-miR-5584-5p antagomir

HY-RI01734

*hsa-miR-5584-3p inhibitor*	MicroRNA	Cancer
hsa-miR-5584-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-5584-3p inhibitor hsa-miR-5584-3p inhibitor

Host:	Mouse (4)
Reactivity:	Human (4) Rat (2) Mouse (2)
Application:	IHC-P (1) ICC/IF (3) WB (3) ELISA (4)
Isotype:	IgG (1) IgG1 (3)
Conjugation:	Non-conjugated (4)
Clonality:	Monoclonal (4)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85992

	Fascin Antibody (YA5684)	IHC-P, ELISA	Human, Mouse, Rat
	Fascin Antibody (YA5684) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Fascin.

HY-P85876

	Galectin-9 Antibody (YA5568)	WB, ICC/IF, ELISA	Human
	Galectin-9 Antibody (YA5568) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Galectin-9.

HY-P85892

	PFKP Antibody (YA5584) PFKP; PFKF; 6-phosphofructokinase type C; 6-phosphofructokinase; platelet type; Phosphofructo-1-kinase isozyme C; PFK-C; Phosphofructokinase 1; Phosphohexokinase	WB, ICC/IF, ELISA	Human, Mouse, Rat
	PFKP Antibody (YA5584) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PFKP.

HY-P85872

	MED1 Antibody (YA5564) Mediator of RNA polymerase II transcription subunit 1; Activator-recruited cofactor 205 kDa component; ARC205; Mediator complex subunit 1; Peroxisome proliferator-activated receptor-binding protein; PBP; PPAR-binding protein; Thyroid hormone receptor-associated protein complex 220 kDa component; Trap220; Thyroid receptor-interacting protein 2; TR-interacting protein 2; TRIP-2; Vitamin D receptor-interacting protein complex component DRIP205;	WB, ICC/IF, ELISA	Human
	MED1 Antibody (YA5564) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MED1.

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Cat. No.	Product Name		Classification

HY-R01763

*hsa-miR-5684* mimic**		MicroRNAs miRNA mimics
hsa-miR-5684 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI01734A

*hsa-miR-5584-3p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5584-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01734

*hsa-miR-5584-3p mimic*		MicroRNAs miRNA mimics
hsa-miR-5584-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01735

*hsa-miR-5584-5p mimic*		MicroRNAs miRNA mimics
hsa-miR-5584-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01763A

*hsa-miR-5684* agomir**		MicroRNAs miRNA agomirs
hsa-miR-5684 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01763A

*hsa-miR-5684* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-5684 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01763

*hsa-miR-5684* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-5684 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01734A

*hsa-miR-5584-3p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5584-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01735

*hsa-miR-5584-5p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5584-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01735A

*hsa-miR-5584-5p agomir*		MicroRNAs miRNA agomirs
hsa-miR-5584-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01735A

*hsa-miR-5584-5p antagomir*		MicroRNAs miRNA antagomirs
hsa-miR-5584-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01734

*hsa-miR-5584-3p inhibitor*		MicroRNAs miRNA inhibitors
hsa-miR-5584-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

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