RABL6 - RAB, member RAS oncogene family like 6 Gene

Also Known as PARF; RBEL1; pp8875; C9orf86

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55684

Summary

This gene encodes a member of the Ras superfamily of small GTPases. The encoded protein binds to both GTP and GDP and may play a role in cell growth and survival. Overexpression of this gene may play a role in Breast Cancer tumorigenesis, and pseudogenes of this gene are located on the long arm of chromosome 2 and the short arm of chromosome 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Ubiquitous expression in colon (RPKM 19.6), prostate (RPKM 17.1) and 25 other tissues.

RABL6 Products (1)

mRNA Protein Name
NG_031950.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTP binding IDA
IDA: Inferred from direct assay
17962191 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12646258 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17962191 GOA
located in nucleus IDA
IDA: Inferred from direct assay
17962191 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RABL6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RABL6 Q3YEC7 MDFI Homo sapiens Q99750
Pull Down
16189514
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11536 RAB26 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11550 RAB36 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11590 RABL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22765 Rabl3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29279 Rabl3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown