MID1IP1 - MID1 interacting protein 1 Gene

Also Known as S14R; MIG12; THRSPL; G12-like; STRAIT11499

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 58526

About MID1IP1

Cytogenetic location: Xp11.4 Genomic coordinates (GRCh38): X:38,801,459-38,806,532 (from NCBI)

This gene has 4 transcripts (splice variants), 183 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 21.2), fat (RPKM 16.5) and 25 other tissues.

Summary

Predicted to enable identical protein binding activity and protein C-terminus binding activity. Predicted to be involved in several processes, including negative regulation of microtubule depolymerization; positive regulation of fatty acid biosynthetic process; and protein polymerization. Predicted to be located in cytoplasm and microtubule Cytoskeleton. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

MID1IP1 Products (3)

mRNA Protein Name
NM_001098790.2 NP_001092260.1 mid1-interacting protein 1
NM_001098791.2 NP_001092261.1 mid1-interacting protein 1
NM_021242.6 NP_067065.1 mid1-interacting protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MID1IP1 Protein Structure

Spot_14

Spot_14: Thyroid hormone-inducible hepatic protein Spot 14 (2 - 183)

  • 0
  • 100
  • 183 a.a.
Protein Preferred Names Protein Names

mid1-interacting protein 1

  • MID1 interacting G12-like protein

MID1IP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MID1IP1 Q9NPA3 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
25416956
Intra
MID1IP1 Q9NPA3 TSHR Homo sapiens P16473
Ub Reconstruction
28298427
Intra
MID1IP1 Q9NPA3 SUFU Homo sapiens Q9UMX1
Anti Tag CoIP
33961781
Intra
MID1IP1 Q9NPA3 AK8 Homo sapiens Q96MA6
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant MID1IP1 Proteins

Cat. No. Product Name Accession Purity
HY-P76497 MID1IP1 Protein, Human (His) Q9NPA3 (M1-H183) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Developmental And Epileptic Encephalopathy 28

  • DEE28

  • Epileptic Encephalopathy, Early Infantile, 28

  • Eiee28

  • Developmental And Epileptic Encephalopathy, 28

  • Early Infantile Epileptic Encephalopathy 28

  • Encephalopathy, Epileptic, Early Infantile, Type 28
Gluten Allergy

  • Allergy To Gluten

  • Gluten Allergic Reaction
Spinocerebellar Ataxia, Autosomal Recessive 12

  • Autosomal Recessive Spinocerebellar Ataxia 12

  • SCAR12

  • Spinocerebellar Ataxia With Mental Retardation And Epilepsy

  • Autosomal Recessive Cerebellar Ataxia-Epilepsy-Intellectual Disability Syndrome Due To Wwox Deficiency

  • Autosomal Recessive Spinocerebellar Ataxia Type 12

  • Spinocerebellar Ataxia, Autosomal Recessive, 12

  • Ataxia, Spinocerebellar, Autosomal Recessive, Type 12
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08435 MID1IP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19281 Mid1ip1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25771 Mid1ip1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MID1IP1 VGNC VGNC:74549
Rattus norvegicus MID1IP1 RGD RGD:1303258
Bos taurus MID1IP1 VGNC VGNC:31465
Felis catus MID1IP1 VGNC VGNC:63497
Canis familiaris MID1IP1 VGNC VGNC:43223
Mus musculus MID1IP1 MGD MGI:1915291
Others MID1IP1 NCBI