9 Results for "

7695

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "7695" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-P7695
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuC5a; Complement C5; Hemolytic Complement; C5a
Species:  
Source:  
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Cat. No.: HY-N7695
CAS No.: 23133-56-4
Physalin B is an orally active anti-inflammatory and anticancer agent. Physalin B can be isolated from Physalis alkekengi L. var. Franchetii. Physalin B inhibits the activation of the NF-κB, NLRP3 inflammasome, STAT3, PI3K/Akt and Hedgehog signaling pathways, regulates the phosphorylation levels of GSK-3β, p38 MAPK, ERK1/2 and JNK, and promotes the nuclear translocation of NRF2. Physalin B reduces the levels of pro-inflammatory cytokines and factors, induces mitochondrial reactive oxygen species (mito-ROS) production, Apoptosis, G2/M cell cycle arrest and incomplete Autophagy, alters cytoskeleton structure and alleviates oxidative stress. Physalin B reduces cancer cell viability, ameliorates liver and lung tissue damage and alleviates liver fibrosis. Physalin B can be used in research related to ulcerative colitis, breast cancer, acute lung injury, colon cancer, non-alcoholic steatohepatitis, liver fibrosis, lung cancer, pancreatic cancer, lymphoma, ovarian cancer, sarcoma and leukemia .
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Cat. No.: HY-P7695A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuC5a; Complement C5; Hemolytic Complement; C5a
Species:  
Source:  
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Cat. No.: HY-R02416
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-769-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
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Cat. No.: HY-163211
CAS No.: 2679814-93-6
Target:  

SARS-CoV

Research Areas:  

Infection

SARS-CoV-2 Mpro-IN-14 (Compound 19) is an inhibitor of SARS-CoV-2 Mpro with an IC50 of 0.044 μM. SARS-CoV-2 Mpro-IN-14 exhibits water solubility, has no cytotoxicity, and can be used in the study of COVID-19 .
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Cat. No.: HY-RI02416
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-769-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
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Cat. No.: HY-R02416A
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-769-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
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Cat. No.: HY-P88010
Synonyms: GLCNE, IBM2, GNE, Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, UDP-GlcNAc-2-epimerase/ManAc kinase

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human

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Cat. No.: HY-RI02416A
Target:  

MicroRNA

Research Areas:  

Cancer

hsa-miR-769-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
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