ZNF136 - zinc finger protein 136 Gene

Also Known as pHZ-20

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7695

Summary

This gene encodes a Zinc Finger Protein containing a Kruppel-associated box (KRAB) A-box domain at its N-terminus, followed by fourteen contiguous C2H2 zinc finger domains and a degenerate zinc finger. The KRAB A-box showed weak transcriptional repressor activity in a reporter gene assay. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]
Ubiquitous expression in thyroid (RPKM 4.2), ovary (RPKM 4.0) and 25 other tissues.

ZNF136 Products (1)

mRNA Protein Name
NG_052983.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
7649249 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF136 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF136 P52737 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
ZNF136 P52737 MTUS2 Homo sapiens Q5JR59-3
Validated Y2H
32296183
Intra
ZNF136 P52737 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
ZNF136 P52737 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
31515488
Intra
ZNF136 P52737 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
Intra
ZNF136 P52737 STX1A Homo sapiens Q16623
Validated Y2H
32296183
Intra
ZNF136 P52737 STX1A Homo sapiens Q16623
Y2H Array
32296183
Intra
ZNF136 P52737 MDFI Homo sapiens Q99750
Validated Y2H
25416956
Intra
ZNF136 P52737 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
ZNF136 P52737 MDFI Homo sapiens Q99750
Y2H
21516116
Intra
ZNF136 P52737 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra
ZNF136 P52737 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
ZNF136 P52737 CEP70 Homo sapiens Q8NHQ1
Validated Y2H
25416956
Intra
ZNF136 P52737 MTUS2 Homo sapiens Q5JR59
Y2H Prey Pooling
25416956
Intra
ZNF136 P52737 MTUS2 Homo sapiens Q5JR59
Validated Y2H
25416956
Intra
ZNF136 P52737 CCNDBP1 Homo sapiens O95273
Y2H Array
31515488
Intra
ZNF136 P52737 CCNDBP1 Homo sapiens O95273
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction