RAB1B - RAB1B, member RAS oncogene family Gene

Homo sapiens

Gene ID: 81876 | Gene type: protein coding

About RAB1B

Cytogenetic location: 11q13.2 Genomic coordinates (GRCh38): 11:66,268,639-66,277,492 (from NCBI)

This gene has 2 transcripts (splice variants), 235 orthologues and 68 paralogues. Ubiquitous expression in prostate (RPKM 64.5), fat (RPKM 64.0) and 25 other tissues.

Summary

Members of the RAB protein family, such as RAB1B, are low molecular mass monomeric GTPases localized on the cytoplasmic surfaces of distinct membrane-bound organelles. RAB1B functions in the early secretory pathway and is essential for vesicle transport between the endoplasmic reticulum (ER) and Golgi (Chen et al., 1997 [PubMed 9030196]; Alvarez et al., 2003 [PubMed 12802079]).[supplied by OMIM, Jan 2009]

RAB1B Products(1)

mRNA	Protein	Name
NM_030981.3	NP_112243.1	ras-related protein Rab-1B

RAB1B Protein Structure

Ras

0
100
201 a.a.

Protein Preferred Names

Protein Names

ras-related protein Rab-1B

small GTP-binding protein

Recombinant RAB1B Proteins

Cat. No.	Product Name	Accession	Purity
HY-P75993	RAB1B Protein, Human (HEK293, Fc)	Q9H0U4 (M1-G199)	≥95%

Related Diseases

Diseases

Alias

Hypotrichosis 3

HYPT3	Hypotrichosis Simplex Of The Scalp 2
Htss2	Hypotrichosis, Type 3

Legionnaire Disease

Legionnaires' Disease	Legionnaires Disease
Legionnaire Disease, Susceptibility To	Legionella
Legionella Pneumonia	Infection By Legionella Pneumophilia
Legionnaire'S Disease	Legionellosis
Legionaire Disease, Susceptibility To	Legionnaires Pneumonia

Legionellosis

Legionella Infection	Pontiac Fever
Legionnaires' Disease	Infection By Legionella Pneumophilia
Legionella Pneumophila Infection

Pontiac Fever

Septicemic Plague

Plague, Septicemic

Immunodeficiency 54

Natural Killer Cell Deficiency, Familial Isolated	Primary Immunodeficiency With Natural-Killer Cell Deficiency And Adrenal Insufficiency
IMD54	Nkcd
Natural Killer Cell And Glucocorticoid Deficiency With Dna Repair Defect	Nkgcd
Familial Isolated Natural Killer Cell Deficiency	Primary Immunodeficiency Due To Mcm4 Deficiency

Warburg Micro Syndrome 1

Warburg Micro Syndrome	Micro Syndrome
Warbm	WARBM1
Warburg Sjo Fledelius Syndrome	Warburg-Sjo-Fledelius Syndrome
Micro Syndrome 1	Microcephaly, Microcornea, Congenital Cataract, Intellectual Disability, Optic Atrophy And Hypogenitalism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11529	RAB1B Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	RAB1B	VGNC	VGNC:56276
Rattus norvegicus	RAB1B	RGD	RGD:1642882
Mus musculus	RAB1B	MGD	MGI:1923558
Canis familiaris	RAB1B	VGNC	VGNC:52037

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