Rab1b Antibody (YA4484)(PBS only)
(Synonyms: Ras-related protein Rab-1B, RAB1B)Rab1b Antibody (YA4484) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Rab1b.
-
Host:
Mouse
-
Isotype:
IgG2b
-
Application:
IHC-P, FC, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS, pH 7.4.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
Rab1b Antibody (YA4484) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Rab1b.
-
Host Mouse
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 41 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 22.2 kDa
Purified recombinant fragment of human Rab1b (AA: 60-201) expressed in E. Coli.
affinity purified.
Non-conjugated
IgG2b
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS, pH 7.4.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
Rab1b is a The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Required to modulate the compacted morphology of the Golgi. Promotes the recruitment of lipid phosphatase MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment[1][2][3][4].
-
Subcellular Localization
Cytoplasm; Membrane; Lipid-anchor; Cytoplasmic side; Preautophagosomal structure membrane; Lipid-anchor; Cytoplasmic side; Cytoplasm, perinuclear region
-
Subunit
Interacts with MICAL1 and MICAL2 (PubMed:15694364, PubMed:27552051). Interacts (in GTP-bound form) with MICALCL, MICAL1 and MILCAL3 (PubMed:15694364, PubMed:27552051).
-
SwissProt ID
-
Synonyms
Ras-related protein Rab-1B, RAB1B
Documentation
Powered by Bioz
