RAB3D - RAB3D, member RAS oncogene family Gene

Also Known as GOV; D2-2; RAB16; RAD3D

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 9545

About RAB3D

Cytogenetic location: 19p13.2 Genomic coordinates (GRCh38): 19:11,322,068-11,339,657 (from NCBI)

This gene has 2 transcripts (splice variants), 259 orthologues and 68 paralogues. Ubiquitous expression in skin (RPKM 24.5), esophagus (RPKM 14.0) and 22 other tissues.

Summary

Enables Myosin V binding activity. Involved in bone resorption and positive regulation of regulated secretory pathway. Located in cytoplasmic microtubule and secretory vesicle. [provided by Alliance of Genome Resources, Apr 2022]

RAB3D Products (1)

mRNA	Protein	Name
NM_004283.4	NP_004274.1	ras-related protein Rab-3D

RAB3D Protein Structure

Ras

0
100
200
219 a.a.

Protein Preferred Names	Protein Names
ras-related protein Rab-3D	Rab3D upregulated with myeloid differentiation

RAB3D Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	RAB3D	O95716	RAB3IP	Homo sapiens	Q96QF0-7	Y2H Prey Pooling	32296183
Intra	RAB3D	O95716	RAB3IP	Homo sapiens	Q96QF0-7	Y2H Array	32296183
Intra	RAB3D	O95716	RAB3IP	Homo sapiens	Q96QF0-7	Validated Y2H	32296183
Intra	RAB3D	O95716	VRTN	Homo sapiens	Q9H8Y1	Validated Y2H	32296183
Intra	RAB3D	O95716	VRTN	Homo sapiens	Q9H8Y1	Y2H Array	32296183
Intra	RAB3D	O95716	VRTN	Homo sapiens	Q9H8Y1	Y2H Prey Pooling	32296183
Intra	RAB3D	O95716	RABIF	Homo sapiens	P47224	Validated Y2H	32296183
Intra	RAB3D	O95716	SYTL4	Homo sapiens	Q96C24	Y2H Prey Pooling	32296183
Intra	RAB3D	O95716	SYTL4	Homo sapiens	Q96C24	Validated Y2H	32296183
Intra	RAB3D	O95716	SYTL4	Homo sapiens	Q96C24	Y2H Array	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases	Alias
Warburg Micro Syndrome 1	Warburg Micro Syndrome Micro Syndrome Warbm WARBM1 Warburg Sjo Fledelius Syndrome Warburg-Sjo-Fledelius Syndrome Micro Syndrome 1 Microcephaly, Microcornea, Congenital Cataract, Intellectual Disability, Optic Atrophy And Hypogenitalism
Dacryoadenitis	Dacryocystitis
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Short-Rib Thoracic Dysplasia 2 With Or Without Polydactyly	Asphyxiating Thoracic Dystrophy 2 SRTD2 Atd2 Jatd Jeune Asphyxiating Thoracic Dystrophy Jeune Syndrome 2
Leukoencephalopathy, Cystic, Without Megalencephaly	Cystic Leukoencephalopathy Without Megalencephaly Rnaset2-Deficient Cystic Leukoencephalopathy Rnase T2-Deficient Leukoencephalopathy Clwm Leukoencephalopathy With Bilateral Anterior Temporal Lobe Cysts Infantile-Onset Rnaset2 Deficient Cystic Leukoencephalopathy Lbatc LCWM
Warburg Micro Syndrome 3	WARBM3 Micro Syndrome 3
Warburg Micro Syndrome 2	WARBM2 Micro Syndrome 2
Martsolf Syndrome 1	Martsolf Syndrome Cataract-Intellectual Disability-Hypogonadism Syndrome MARTS1 Marts Cataract-Mental Retardation-Hypogonadism Martsolf

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11558	RAB3D Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	RAB3D	VGNC	VGNC:81542
Felis catus	RAB3D	VGNC	VGNC:102699
Canis familiaris	RAB3D	VGNC	VGNC:45285
Mus musculus	RAB3D	MGD	MGI:97844
Bos taurus	RAB3D	VGNC	VGNC:33652
Rattus norvegicus	RAB3D	RGD	RGD:620924
Others	RAB3D	NCBI