2 Results for "

glucosyl-vitexin

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "glucosyl-vitexin" in MCE Product Catalog:

1
Vitexin 4'-glucoside
Vitexin 4'-glucoside
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1 Cited Publications
Cat. No.: HY-N4085
CAS No.: 38950-94-6
Synonyms: 4'-O-glucosylvitexin
Category:  

other families Flavonoids Flavones Metabolic Disease Phenols Polyphenols Plants Disease Research Fields

Target:  

Others

Vitexin 4'-glucoside is a leaf flavonoid identified from Briza stricta .
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Vitexin-4''-O-glucoside
Vitexin-4''-O-glucoside
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Cat. No.: HY-N5073
CAS No.: 178468-00-3
Synonyms: 4''-O-glucosylvitexin
Category:  

Cardiovascular Disease Flavonoids Flavones Rosaceae Phenols Polyphenols Crataegus pinnatifida Bge. Plants Disease Research Fields

Target:  

JNK p38 MAPK Interleukin Related TNF Receptor Caspase Lactate Dehydrogenase Apoptosis

Vitexin-4''-O-glucoside (4''-O-Glucosylvitexin) is an orally active natural flavonoid component with multiple pharmacological effects including antioxidation, anti-inflammation, cytoprotection and anti-apoptosis. Vitexin-4''-O-glucoside regulates the MAPK signaling pathway by downregulating the phosphorylation levels of JNK and p38, thereby blocking endoplasmic reticulum stress responses. Vitexin-4''-O-glucoside alleviates oxidative stress by reducing MDA content and upregulating the activities of SOD and CAT, attenuates inflammation by downregulating the expressions of inflammatory factors TNF-α, IL-1β and IL-6, and also reduces LDH release and inhibits caspase-3 activation. Vitexin-4''-O-glucoside effectively improves drug-induced acute liver injury and exerts significant protective effects against myocardial hypoxia/reoxygenation injury. Vitexin-4''-O-glucoside can be used in studies on acute liver injury, cardiovascular diseases and myocardial hypoxia-reoxygenation injury .
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