MK-8325
MK-8325 (Compound 1) is an orally active HCV NS5A inhibitor. MK-8325 exhibits minimal inhibitory activity against hERG at a concentration of 30 mM. MK-8325 may be used in hepatitis C research.
For research use only. We do not sell to patients.
- CAS No.: 1334312-52-5
- Formula: C43H52F2N8O6Si
- Molecular Weight:843.01
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>25 μM
Compound: 1; MK-8325
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Cytotoxicity in human HuH7 replicon cells by MTS assay
Cytotoxicity in human HuH7 replicon cells by MTS assay
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[PMID: 29653894] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1334312-52-5
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Molecular Weight 843.01
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Formula C43H52F2N8O6Si
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SMILES
O=C(OC)N[C@@H](C(C)C)C(N1C[Si](C)(C)C[C@H]1C2=NC3=CC=C4C=C(C5=CC=C(C6=CN=C([C@H]7N(C([C@H](C(C)C)NC(OC)=O)=O)CC(F)(F)C7)N6)C=C5)C=CC4=C3N2)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MK-8325 Related Classifications
HY-123808 Related Classifications
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