Antioxidant 1010
Based on 1 Customer Validation
Antioxidant 1010 (lrganox 1010; AT1010) is a hindered phenolic antioxidant. Antioxidant 1010 does not inhibit intercellular gap-junctional communication. Antioxidant 1010 exhibits antioxidant efficacy in plastic, rubber and synthetic fiber.
For research use only. We do not sell to patients.
- Purity: 98.04%
- CAS No.: 6683-19-8
- Formula: C73H108O12
- Molecular Weight:1177.66
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Antioxidant 1010 (7 days) does not inhibit intercellular gap-junctional communication in Chinese hamster V79 lung fibroblasts in the MC assay at any tested concentration[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6683-19-8
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Appearance Solid
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Molecular Weight 1177.66
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Formula C73H108O12
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Color White to off-white
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SMILES
O=C(OCC(COC(CCC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)=O)(COC(CCC2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2)=O)COC(CCC3=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C3)=O)CCC4=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C4
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Synonyms
lrganox 1010; AT1010
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (169.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (276 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.8491 mL | 4.2457 mL | 8.4914 mL | 21.2285 mL |
| 5 mM | 0.1698 mL | 0.8491 mL | 1.6983 mL | 4.2457 mL | |
| 10 mM | 0.0849 mL | 0.4246 mL | 0.8491 mL | 2.1229 mL | |
| 15 mM | 0.0566 mL | 0.2830 mL | 0.5661 mL | 1.4152 mL | |
| 20 mM | 0.0425 mL | 0.2123 mL | 0.4246 mL | 1.0614 mL | |
| 25 mM | 0.0340 mL | 0.1698 mL | 0.3397 mL | 0.8491 mL | |
| 30 mM | 0.0283 mL | 0.1415 mL | 0.2830 mL | 0.7076 mL | |
| 40 mM | 0.0212 mL | 0.1061 mL | 0.2123 mL | 0.5307 mL | |
| 50 mM | 0.0170 mL | 0.0849 mL | 0.1698 mL | 0.4246 mL | |
| 60 mM | 0.0142 mL | 0.0708 mL | 0.1415 mL | 0.3538 mL | |
| 80 mM | 0.0106 mL | 0.0531 mL | 0.1061 mL | 0.2654 mL | |
| 100 mM | 0.0085 mL | 0.0425 mL | 0.0849 mL | 0.2123 mL |
- Antioxidant 1010
- 6683-19-8
- lrganox 1010
- AT1010
- Antioxidant1010
- Antioxidant-1010
- lrganox1010
- lrganox-1010
- AT1010
- AT 1010
- AT-1010
- Environmental Pollutants
- Biochemical Assay Reagents
- hindered phenolic antioxidant
- ethanol
- intercellular gap-junctional communication
- 2-butanol
- Chinese hamster V79 lung fibroblasts
- methanol
- 1-butanol
- 2-methyl-1-propanol
- 1-propanol
- 2-propanol
- Inhibitor
- inhibitor
- inhibit