Kat7 - K(lysine) acetyltransferase 7 Gene

Also Known as Hbo1; Hboa; Myst2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 217127

Summary

Enables Histone Acetyltransferase activity. Involved in several processes, including histone H3-K14 acetylation; positive regulation of erythrocyte differentiation; and positive regulation of transcription, DNA-templated. Located in nucleus. Part of histone H3-K14 acetyltransferase complex. Is expressed in brain; early conceptus; genitourinary system; and limb. Orthologous to human KAT7 (lysine acetyltransferase 7). [provided by Alliance of Genome Resources, Apr 2022]

Kat7 Products (37)

mRNA Protein Name
NM_001195003.2 NP_001181932.1 histone acetyltransferase KAT7 isoform 1
NM_001195004.2 NP_001181933.1 histone acetyltransferase KAT7 isoform 2
NM_001405194.1 NP_001392123.1 histone acetyltransferase KAT7 isoform 4
NM_001405195.1 NP_001392124.1 histone acetyltransferase KAT7 isoform 5
NM_001405196.1 NP_001392125.1 histone acetyltransferase KAT7 isoform 6
NM_001405197.1 NP_001392126.1 histone acetyltransferase KAT7 isoform 7
NM_001405198.1 NP_001392127.1 histone acetyltransferase KAT7 isoform 8
NM_001405199.1 NP_001392128.1 histone acetyltransferase KAT7 isoform 9
NM_001405200.1 NP_001392129.1 histone acetyltransferase KAT7 isoform 10
NM_001405201.1 NP_001392130.1 histone acetyltransferase KAT7 isoform 11
NM_001405202.1 NP_001392131.1 histone acetyltransferase KAT7 isoform 12
NM_001405203.1 NP_001392132.1 histone acetyltransferase KAT7 isoform 13
NM_001405204.1 NP_001392133.1 histone acetyltransferase KAT7 isoform 14
NM_001405205.1 NP_001392134.1 histone acetyltransferase KAT7 isoform 15
NM_001405206.1 NP_001392135.1 histone acetyltransferase KAT7 isoform 16
NM_001405207.1 NP_001392136.1 histone acetyltransferase KAT7 isoform 17
NM_001405208.1 NP_001392137.1 histone acetyltransferase KAT7 isoform 18
NM_001405209.1 NP_001392138.1 histone acetyltransferase KAT7 isoform 19
NM_001405210.1 NP_001392139.1 histone acetyltransferase KAT7 isoform 20
NM_001405211.1 NP_001392140.1 histone acetyltransferase KAT7 isoform 21
NM_001405212.1 NP_001392141.1 histone acetyltransferase KAT7 isoform 22
NM_001405213.1 NP_001392142.1 histone acetyltransferase KAT7 isoform 23
NM_001405214.1 NP_001392143.1 histone acetyltransferase KAT7 isoform 24
NM_001405215.1 NP_001392144.1 histone acetyltransferase KAT7 isoform 25
NM_001405216.1 NP_001392145.1 histone acetyltransferase KAT7 isoform 21
NM_001405217.1 NP_001392146.1 histone acetyltransferase KAT7 isoform 21
NM_001405218.1 NP_001392147.1 histone acetyltransferase KAT7 isoform 21
NM_001405219.1 NP_001392148.1 histone acetyltransferase KAT7 isoform 21
NM_001405220.1 NP_001392149.1 histone acetyltransferase KAT7 isoform 22
NM_001405221.1 NP_001392150.1 histone acetyltransferase KAT7 isoform 22
NM_001405222.1 NP_001392151.1 histone acetyltransferase KAT7 isoform 22
NM_001405223.1 NP_001392152.1 histone acetyltransferase KAT7 isoform 22
NM_001405224.1 NP_001392153.1 histone acetyltransferase KAT7 isoform 22
NM_001405225.1 NP_001392154.1 histone acetyltransferase KAT7 isoform 23
NM_001405226.1 NP_001392155.1 histone acetyltransferase KAT7 isoform 25
NM_001405227.1 NP_001392156.1 histone acetyltransferase KAT7 isoform 26
NM_177619.4 NP_808287.1 histone acetyltransferase KAT7 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables histone H3K14 acetyltransferase activity IDA
IDA: Inferred from direct assay
21753189 MGI
enables histone H3K14 acetyltransferase activity IMP
IMP: Inferred from mutant phenotype
21149574 MGI
Biological Process GO Annotation Evidence References Source
involved in T cell differentiation IMP
IMP: Inferred from mutant phenotype
27733580 MGI
involved in natural killer cell differentiation IMP
IMP: Inferred from mutant phenotype
27733580 MGI
involved in positive regulation of DNA-templated transcription, elongation IDA
IDA: Inferred from direct assay
31827282 MGI
involved in positive regulation of erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
21753189 MGI
involved in positive regulation of hematopoietic stem cell proliferation IDA
IDA: Inferred from direct assay
31827282 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
21149574 MGI
involved in transcription initiation-coupled chromatin remodeling IMP
IMP: Inferred from mutant phenotype
21149574 MGI
Cellular Component GO Annotation Evidence References Source
part of histone H3-K14 acetyltransferase complex IDA
IDA: Inferred from direct assay
21753189 MGI
located in nucleus IDA
IDA: Inferred from direct assay
21149574 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone acetyltransferase KAT7

  • MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2

  • MYST histone acetyltransferase 2

  • histone acetyltransferase MYST2

  • histone acetyltransferase binding to ORC1

  • lysine acetyltransferase 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-134901 WM-3835 99.78% Unkown
HY-102058 WM-1119 Inhibitor 99.57% Unkown
HY-176244 KI-TOX-A3 Inhibitor 99.15% Unkown
HY-168428 CHI-KAT8i5 98.00% Unkown
HY-177046 KAT6A/KAT7-IN-4 Inhibitor 98.86% Unkown
HY-177045 KAT6A/KAT7-IN-3 Inhibitor / Unkown
HY-RS07083 KAT7 Human Pre-designed siRNA Set A / Unkown
HY-RS16911 Kat7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-177043 KAT6A/KAT7-IN-1 Inhibitor / Unkown
HY-177044 KAT6A/KAT7-IN-2 Inhibitor / Unkown
HY-RS23353 Kat7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kat7 NCBI NCBI:11143