PDE2A - phosphodiesterase 2A Gene

Also Known as cGSPDE; CGS-PDE

Species: Bos taurus

Gene Type: protein coding
Gene ID: 281971

About PDE2A

Primary_assembly 15: 52,090,857-52,228,534 reverse strand.ARS-UCD1.2:CM008182.2

This gene has 7 transcripts (splice variants), 215 orthologues and 21 paralogues.

PDE2A Products (2)

mRNA Protein Name
NM_001256273.1 NP_001243202.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform PDE2A1
NM_001143846.1 NP_001137318.1 cGMP-dependent 3',5'-cyclic phosphodiesterase isoform PDE2A3

PDE2A Protein Structure

GAF

GAF: smart00065 (320 - 467)

GAF

GAF: smart00065 (489 - 638)

PDEase_I

PDEase_I: pfam00233 (735 - 968)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1022 a.a.
Protein Preferred Names Protein Names

cGMP-dependent 3',5'-cyclic phosphodiesterase

  • c-GMP stimulated phosphodiesterase

  • cyclic GMP-stimulated phosphodiesterase

  • phosphodiesterase 2A, cGMP-stimulated

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-112831 Osoresnontrine Inhibitor 99.94% Phase 2
HY-111167 AN-2898 Inhibitor / Phase 2
HY-111371 PF-05180999 Inhibitor 99.96% Phase 1
HY-103493 TAK-915 Inhibitor 99.57% Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-102050 PF-05085727 Inhibitor 99.53% Unkown
HY-132993 Hcyb1 Inhibitor 98.20% Unkown
HY-U00427 PDE2A-IN-3 Inhibitor 99.88% Unkown
HY-102043 PDM-631 Inhibitor / Unkown
HY-112704 PDE5-IN-2 Inhibitor / Unkown
HY-120710 DNS-8254 Inhibitor / Unkown
HY-142660 PDE2A-IN-1 Inhibitor / Unkown
HY-168966 JNJ-54082730 / Unkown
HY-180526 PDE2A-IN-2 Inhibitor / Unkown
HY-RS10213 PDE2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10214 Pde2a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10215 Pde2a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-124173 PF-06815189 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE2A NCBI NCBI:5138