DPPE-PEG5000-N3
DPPE-PEG5000-N3 (DPPE-PEG5000-Azide) is a conjugate composed of DPPE, PEG chains, and terminal azido groups (-N3). DPPE-PEG5000-Azide is a click chemistry reagent used for the targeted modification of liposomes/nanoparticles.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
DPPE-PEG5000-Azide is used as a core component in the preparation of liposomes or lipid nanoparticles (LNPs) to encapsulate drugs or genes. Containing the Azide group, DPPE-PEG5000-Azide can undergo a copper-catalyzed azido-alkynylene cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo a ring-strain-driven alkynylene-azido cycloaddition reaction (SPAAC) with molecules containing DBCO or BCN groups.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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SMILES
CCCCCCCCCCCCCCCC(OC[C@@](COP(O)(OCCNC(OCCOCCN=[N+]=[N-])=O)=O)([H])OC(CCCCCCCCCCCCCCC)=O)=O.[n]
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Synonyms
DPPE-PEG5000-Azide
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)