Fosfenopril (Standard)
Fosfenopril (Standard) is the analytical standard of Fosfenopril. This product is intended for research and analytical applications. Fosfenopril (Fosinoprilat) is a potent angiotensin converting enzyme (ACE) inhibitor. Fosfenopril alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 95399-71-6
- Formula: C23H34NO5P
- Molecular Weight:435.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 95399-71-6
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Molecular Weight 435.49
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Formula C23H34NO5P
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SMILES
O=P(CCCCC1=CC=CC=C1)(O)CC(N2C[C@H](C3CCCCC3)C[C@H]2C(O)=O)=O
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Synonyms
Fosinoprilat (Standard); Fosinoprilic acid (Standard); SQ 27519 (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Yang S, et al. Fosinoprilat alleviates lipopolysaccharide (LPS)-induced inflammation by inhibiting TLR4/NF-κB signaling in monocytes. Cell Immunol. 2013 Jul-Aug;284(1-2):182-6. [Content Brief]
[2]. DeForrest JM, et al. Fosinopril, a phosphinic acid inhibitor of angiotensin I converting enzyme: in vitro and preclinical in vivo pharmacology. J Cardiovasc Pharmacol. 1989 Nov;14(5):730-6. [Content Brief]
[3]. DeForrest JM, et al. Blood pressure lowering and renal hemodynamic effects of fosinopril in conscious animal models. J Cardiovasc Pharmacol. 1990 Jul;16(1):139-46. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Fosfenopril (Standard)
- 95399-71-6
- Fosinoprilat (Standard)
- Fosinoprilic acid (Standard)
- SQ 27519 (Standard)
- Reference Standards
- Angiotensin-converting Enzyme (ACE)
- Toll-like Receptor (TLR)
- NF-κB
- TNF Receptor
- Interleukin Related
- Anti-atherosclerosis
- Fosinoprilat
- Lipopolysacharides
- Toll-like receptors
- Inhibitor
- inhibitor
- inhibit