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Cat. No.: HY-111896A

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(-)-7-Methoxyrosmanol

(Synonyms: (-)-7-O-Methoxyrosmanol)

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(-)-7-Methoxyrosmanol ((-)-7-O-Methoxyrosmanol) is a phenolic diterpene with antioxidant activity. (-)-7-Methoxyrosmanol is produced from carnosic acid by oxidation and cyclization, can induce cell cycle arrest and apoptosis in neuroblastoma cells.

For research use only. We do not sell to patients.

Purity: 99.53%
CAS No.: 24703-38-6
Formula: C₂₁H₂₈O₅
Molecular Weight:360.44

Storage:

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

(-)-7-Methoxyrosmanol Chemical Structure

CAS No.: 24703-38-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
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Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	35.6 μM Compound: 7	Cytotoxicity against human A549 cells at lag phase of growth after 48 hrs by MTT assay Cytotoxicity against human A549 cells at lag phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
A549	IC₅₀	50.8 μM Compound: 7	Cytotoxicity against human A549 cells at exponential phase of growth after 48 hrs by MTT assay Cytotoxicity against human A549 cells at exponential phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
HeLa	IC₅₀	>60 μM Compound: 7	Cytotoxicity against human HeLa cells at exponential phase of growth after 48 hrs by MTT assay Cytotoxicity against human HeLa cells at exponential phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
HeLa	IC₅₀	40.8 μM Compound: 7	Cytotoxicity against human HeLa cells at lag phase of growth after 48 hrs by MTT assay Cytotoxicity against human HeLa cells at lag phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
MCF7	IC₅₀	23.3 μM Compound: 7	Cytotoxicity against human MCF7 cells at lag phase of growth after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells at lag phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
MCF7	IC₅₀	41.1 μM Compound: 7	Cytotoxicity against human sMCF7 cells at exponential phase of growth after 48 hrs by MTT assay Cytotoxicity against human sMCF7 cells at exponential phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
Vero	IC₅₀	33.9 μM Compound: 7	Cytotoxicity against african green monkey Vero cells at exponential phase of growth after 48 hrs by MTT assay Cytotoxicity against african green monkey Vero cells at exponential phase of growth after 48 hrs by MTT assay	[PMID: 19711987]
Vero	IC₅₀	36.7 μM Compound: 7	Cytotoxicity against african green monkey Vero cells at lag phase of growth after 48 hrs by MTT assay Cytotoxicity against african green monkey Vero cells at lag phase of growth after 48 hrs by MTT assay	[PMID: 19711987]

Chemical Information

CAS No. 24703-38-6
Appearance Solid
Molecular Weight 360.44
Formula C₂₁H₂₈O₅
SMILES

O=C1[C@]23[C@@](C(C)(CCC3)C)([H])[C@@H]([C@@H](C4=CC(C(C)C)=C(O)C(O)=C42)OC)O1.[Rotation (-)]
Synonyms

(-)-7-O-Methoxyrosmanol
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tabata K, et al. Phenolic diterpenes derived from Hyptis incana induce apoptosis and G(2)/M arrest of neuroblastoma cells. Anticancer Res. 2012 Nov;32(11):4781-9. [Content Brief]

[2]. Jiang Z Y, et al. Perovskatone A: a novel C23 terpenoid from Perovskia atriplicifolia[J]. Tetrahedron letters, 2013, 54(29): 3886-3888.

[3]. Richheimer S L, et al. Antioxidant activity of lipid-soluble phenolic diterpenes from rosemary[J]. Journal of the American Oil Chemists’ Society, 1996, 73(4): 507-514.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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(-)-7-Methoxyrosmanol

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(-)-7-Methoxyrosmanol

Antioxidant Compound Library

Terpenoids Library

Plant-Sourced Natural Product Library

Radioprotector Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Natural Product Library Plus

Bioactive Compound Library

Anti-Fibrosis Compound Library

High-Throughput Bioactive Compound Library

High-Throughput Natural Product Library

Mass Spectrometry Natural Product Library

Natural Product and Natural Product-Like Compound Library

Natural Product Library

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Chemical Information

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Help & FAQs

(-)-7-Methoxyrosmanol Related Classifications

HY-111896A Related Classifications