24-Epicastasterone
Based on 2 publication(s) in Google Scholar
24-Epicastasterone (24-epi-Castasterone) is a bioactive brassinosteroid and a ligand of ABCB1 and ABCB19 in Arabidopsis thaliana. 24-Epicastasterone stimulates the ATPase activity of ABCB19 and the ATP hydrolysis activity of ABCB1, which drive the efflux of substances from plant cells. 24-Epicastasterone increases the activities of catalase and guaiacol peroxidase in the roots of wheat seedlings. 24-Epicastasterone alleviates heat-induced lipid peroxidation through a ROS-dependent mechanism and enhances the heat tolerance of common wheat seedlings.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.91%
- CAS 番号: 72050-71-6
- 分子式: C28H48O5
- 分子量:464.68
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 24-Epicastasterone
More
生物活性
24-epicastasterone (20 min pre-incubation on ice, 10 min reaction at 37°C) potently stimulates the ATPase activity of purified Arabidopsis ABCB19 protein in a dose-dependent manner[1].
24-epicastasterone (0.05 mM) binds directly to purified Arabidopsis ABCB19 protein reconstituted in amphipols with a dissociation constant of 0.36 μM[1].
24-Epicastasterone (1 μM; foliar spray; once daily; 11 consecutive days) rescues growth in brassinosteroid-deficient Arabidopsis biosynthetic mutants but not in ABCB19 transporter-deficient mutants, confirming ABCB19 is required for functional 24-epicastasterone signaling[1].
24-epicastasterone (5-200 nM; 24 h) increases the heat resistance of Triticum aestivum cv. Doskonala wheat seedlings, with the most significant effect observed at a 50 nM concentration applied for 24 h, and a significant effect also seen at 20 nM[2].
24-epicastasterone (50 nM; 2 h, 4 h, 24 h) modulates the activity of superoxide dismutase, catalase, and guaiacol peroxidase in roots of Triticum aestivum cv. Doskonala wheat seedlings, with superoxide dismutase activity elevated at 4 h, catalase activity elevated at 24 h, and guaiacol peroxidase activity elevated at 4 h but not significantly different from control at 24 h[2].
24-epicastasterone (50 nM; 24 h before heat stress) reduces heat-induced lipid peroxidation in roots of Triticum aestivum cv. Doskonala wheat seedlings, an effect dependent on NADPH oxidase-mediated hydrogen peroxide production[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 72050-71-6
-
性状 Solid
-
分子量 464.68
-
分子式 C28H48O5
-
Color Off-white to light brown
-
SMILES
C[C@@]12[C@]3([H])[C@](CC([C@@]1([H])C[C@@H]([C@@H](C2)O)O)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)[C@@H](O)[C@H](O)[C@H](C)C(C)C)C
-
別名
24-epi-Castasterone
-
Initial Source
Hydrodictyon reticulatum
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (2)
-
Journal Impact Factor
-
Most Recent
-
Science
Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export. [Abstract]2024 Mar 22;383(6689):eadj4591. PMID: 38513023 -
Plant Commun
Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1. [Abstract]2025 Jan 13;6(1):101181. PMID: 39497419
溶剤 & 溶解度
THF : 10 mg/mL (21.52 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (276 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. Ying W, et al. Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export. Science. 2024 Mar 22;383(6689):eadj4591. [Content Brief]
[3]. Wei H, et al. Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1. Plant Commun. 2025;6(1):101181. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| THF | 1 mM | 2.1520 mL | 10.7601 mL | 21.5202 mL | 53.8005 mL |
| 5 mM | 0.4304 mL | 2.1520 mL | 4.3040 mL | 10.7601 mL | |
| 10 mM | 0.2152 mL | 1.0760 mL | 2.1520 mL | 5.3800 mL | |
| 15 mM | 0.1435 mL | 0.7173 mL | 1.4347 mL | 3.5867 mL | |
| 20 mM | 0.1076 mL | 0.5380 mL | 1.0760 mL | 2.6900 mL |
24-Epicastasterone 関連分類
HY-N10455 関連分類
Powered by Bioz