72050-71-6
Chemical Structure
24-Epicastasterone
Synonym(s): 24-epi-Castasterone
- CAS No.: 72050-71-6
- Formula:C28H48O5
- Molecular Weight:464.68
IUPAC Name: 4,4-difluorotetrahydro-2H-pyran-3-carboxylic acid
InChIKey: VYUIKSFYFRVQLF-QONPFPPSSA-N
SMILES: C[C@@]12[C@]3([H])[C@](CC([C@@]1([H])C[C@@H]([C@@H](C2)O)O)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)[C@@H](O)[C@H](O)[C@H](C)C(C)C)C
Biological Activity: 24-Epicastasterone (24-epi-Castasterone) is a bioactive brassinosteroid and a ligand of ABCB1 and ABCB19 in Arabidopsis thaliana. 24-Epicastasterone stimulates the ATPase activity of ABCB19 and the ATP hydrolysis activity of ABCB1, which drive the efflux of substances from plant cells. 24-Epicastasterone increases the activities of catalase and guaiacol peroxidase in the roots of wheat seedlings. 24-Epicastasterone alleviates heat-induced lipid peroxidation through a ROS-dependent mechanism and enhances the heat tolerance of common wheat seedlings[1][2][3].
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24-Epicastasterone | 99.91% | 24-Epicastasterone (24-epi-Castasterone) is a bioactive brassinosteroid and a ligand of ABCB1 and ABCB19 in Arabidopsis thaliana. 24-Epicastasterone stimulates the ATPase activity of ABCB19 and the ATP hydrolysis activity of ABCB1, which drive the efflux of substances from plant cells. 24-Epicastasterone increases the activities of catalase and guaiacol peroxidase in the roots of wheat seedlings. 24-Epicastasterone alleviates heat-induced lipid peroxidation through a ROS-dependent mechanism and enhances the heat tolerance of common wheat seedlings. | ||||||||||||||||||||
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- [1]. Ying W, et al. Structure and function of the Arabidopsis ABC transporter ABCB19 in brassinosteroid export. Science. 2024 Mar 22;383(6689):eadj4591. [Content Brief]
- [2]. Litvinovskaya, R.P., et al. ROS-Dependent Stress-Protective Effect of 24-Epicastasterone and Its Monosalicylate on Wheat Seedlings in Hyperthermia. Appl Biochem Microbiol 57, 770–777 (2021).
- [3]. Wei H, et al. Structural insights into brassinosteroid export mediated by the Arabidopsis ABC transporter ABCB1. Plant Commun. 2025;6(1):101181. [Content Brief]
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