28-Homobrassinolide
Based on 3 publication(s) in Google Scholar
28-Homobrassinolide is a phytosteroid. 28-Homobrassinolide can be used for the research of cholesterol and glucose homeostasis.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 82373-95-3
- Formula: C29H50O6
- Molecular Weight:494.70
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) 28-Homobrassinolide
More
Biological Activity
28-Homobrassinolide (5-20 μM) indicates a 2-fold increase in glucose utilization and ABCA1 and SREBP2 protein expression in HepG2 cells[1].
28-Homobrassinolide decreases tissue glucose and cholesterol levels, increases cholesterol level and tissue hexokinase activity[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HepG2 cells
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Concentration:1 µM, 5 µM, 10 µM, 20 µM, 30 µM, 40 µM, and 80 µM
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Incubation Time:24 h
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Result:The IC50 value of 40.57µM obtained by the MTT assay.
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Cell Line:HepG2 cells
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Concentration:5, 10, and 20 μM
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Incubation Time:12 h
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Result:Exhibited an increase in both ABCA1 and SREBP2 markers.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:High-fat diet-fed C57BL/6 mice[1]
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Dosage:1-20 μg/day
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Administration:For 6 weeks
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Result:Observed a significant decrease in lipid deposition.
Chemical Information
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CAS No. 82373-95-3
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Appearance Solid
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Molecular Weight 494.70
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Formula C29H50O6
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Color White to off-white
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)[C@@H](O)[C@H](O)[C@@H](CC)C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@@](C[C@@H]([C@@H](C4)O)O)([H])C(OC3)=O)C
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (3)
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Journal Impact Factor
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Most Recent
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Plant Commun
Brassinosteroid signaling regulates PIN5/10-mediated intracellular auxin homeostasis to promote lateral root development in tomato. [Abstract]2026 Mar 16:101823. PMID: 41846312 -
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Solvent & Solubility
DMSO : 20 mg/mL (40.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0214 mL | 10.1071 mL | 20.2143 mL | 50.5357 mL |
| 5 mM | 0.4043 mL | 2.0214 mL | 4.0429 mL | 10.1071 mL | |
| 10 mM | 0.2021 mL | 1.0107 mL | 2.0214 mL | 5.0536 mL | |
| 15 mM | 0.1348 mL | 0.6738 mL | 1.3476 mL | 3.3690 mL | |
| 20 mM | 0.1011 mL | 0.5054 mL | 1.0107 mL | 2.5268 mL | |
| 25 mM | 0.0809 mL | 0.4043 mL | 0.8086 mL | 2.0214 mL | |
| 30 mM | 0.0674 mL | 0.3369 mL | 0.6738 mL | 1.6845 mL | |
| 40 mM | 0.0505 mL | 0.2527 mL | 0.5054 mL | 1.2634 mL |
28-Homobrassinolide Related Classifications
HY-N9435 Related Classifications
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