(22S,23S)-Homobrassinolide
Based on 1 Customer Validation
(22S,23S)-Homobrassinolide is one of the most active brassinosteroids in inducing plant growth in various plant bioassay systems. (22S,23S)-Homobrassinolide shows Akt-dependent anabolic activity in rat skeletal muscle cells. Orally active.
For research use only. We do not sell to patients.
- Purity : 99.80%
- CAS No.: 80483-89-2
- Formula: C29H50O6
- Molecular Weight:494.70
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-112102R
(22S,23S)-Homobrassinolide (Standard) -
HY-N0848
Epibrassinolide -
HY-19700
trans-Zeatin -
HY-W011209
N6-Isopentenyladenosine -
HY-W131845
Ethephon -
HY-129038
GR24 -
HY-B0872
Thidiazuron -
HY-N2489
5α-Hydroxy-laxogenin -
HY-W013507
(rac)-Methyl jasmonate -
HY-126823
Phen Green SK diacetate (5/6-mixture) -
HY-W013507R
(rac)-Methyl jasmonate (Standard) -
HY-W131845R
Ethephon (Standard)
All Endogenous Metabolite Isoforms
More
Biological Activity
Description
In Vitro
(22S,23S)-Homobrassinolide slightly stimulates ferricyanide reduction and promotes uptake of sucrose and alpha-aminoisobutyric acid [2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 80483-89-2
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Appearance Solid
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Molecular Weight 494.70
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Formula C29H50O6
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Color White to off-white
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SMILES
C[C@@]12[C@](CC[C@]2([H])[C@H](C)[C@H](O)[C@@H](O)[C@@H](CC)C(C)C)([H])[C@@]3([H])[C@]([C@@]4([C@@](C[C@H](O)[C@H](O)C4)([H])C(OC3)=O)C)([H])CC1
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Synonyms
SSHB
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (202.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Esposito D, et al. Akt-dependent anabolic activity of natural and synthetic brassinosteroids in rat skeletal muscle cells. J Med Chem. 2011;54(12):4057-4066. [Content Brief]
[2]. Dahse I, et al. Effects of (22S,23S)-Homobrassinolide and Related Compounds on Membrane Potential and Transport of Egeria Leaf Cells. Plant Physiol. 1990;93(3):1268-1271. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.0214 mL | 10.1071 mL | 20.2143 mL | 50.5357 mL |
| 5 mM | 0.4043 mL | 2.0214 mL | 4.0429 mL | 10.1071 mL | |
| 10 mM | 0.2021 mL | 1.0107 mL | 2.0214 mL | 5.0536 mL | |
| 15 mM | 0.1348 mL | 0.6738 mL | 1.3476 mL | 3.3690 mL | |
| 20 mM | 0.1011 mL | 0.5054 mL | 1.0107 mL | 2.5268 mL | |
| 25 mM | 0.0809 mL | 0.4043 mL | 0.8086 mL | 2.0214 mL | |
| 30 mM | 0.0674 mL | 0.3369 mL | 0.6738 mL | 1.6845 mL | |
| 40 mM | 0.0505 mL | 0.2527 mL | 0.5054 mL | 1.2634 mL | |
| 50 mM | 0.0404 mL | 0.2021 mL | 0.4043 mL | 1.0107 mL | |
| 60 mM | 0.0337 mL | 0.1685 mL | 0.3369 mL | 0.8423 mL | |
| 80 mM | 0.0253 mL | 0.1263 mL | 0.2527 mL | 0.6317 mL | |
| 100 mM | 0.0202 mL | 0.1011 mL | 0.2021 mL | 0.5054 mL |
(22S,23S)-Homobrassinolide Related Classifications
HY-112102 Related Classifications
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