AChE-IN-90
AChE-IN-90 (Compound 5b) is an orally active, brain-penetrant and potent acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.023 μM against human AChE and lower selectivity for butyrylcholinesterase (BuChE) (IC50 1.8 μM). AChE-IN-90 increases acetylcholine levels in the synaptic cleft. AChE-IN-90 is promising for research of neurodegenerative diseases such as Alzheimer's disease.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C19H25ClN2O3
- 分子量:364.87
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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hAChE 0.023 μM (IC50) |
化学情報
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分子量 364.87
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分子式 C19H25ClN2O3
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SMILES
O=C(OC(C)(C)C)NC1CN(C(/C=C/C2=CC=CC=C2Cl)=O)CCC1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)