country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-158436

Copy Link Print Information

Antitumor agent-155

Antitumor agent-155 (Compound 13) inhibits microtubule polymerization, induces autophagy and apoptosis. Antitumor agent-155 shows cytotoxicity against HCT116, A549, AGS, SK-MES-1 cells with IC₅₀s of 0.227, 0.253, 0.574, 0.423 μM respectively.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 3044017-96-8
分子式: C₃₀H₃₄N₂O₆
分子量:518.60

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Antitumor agent-155 構造式

CAS 番号: 3044017-96-8

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.253 μM Compound: 13	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay	[PMID: 38759453]
AGS	IC₅₀	0.574 μM Compound: 13	Cytotoxicity against human AGS cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay Cytotoxicity against human AGS cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay	[PMID: 38759453]
HCT-116	IC₅₀	0.227 μM Compound: 13	Cytotoxicity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay Cytotoxicity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay	[PMID: 38759453]
NCM460	IC₅₀	1.09 μM Compound: 13	Cytotoxicity against human NCM460 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay Cytotoxicity against human NCM460 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay	[PMID: 38759453]
SK-MES-1	IC₅₀	0.423 μM Compound: 13	Cytotoxicity against human SK-MES-1 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay Cytotoxicity against human SK-MES-1 cells assessed as inhibition of cell proliferation measured after 72 hrs by CCK-8 assay	[PMID: 38759453]

化学情報

CAS 番号 3044017-96-8
分子量 518.60
分子式 C₃₀H₃₄N₂O₆
SMILES

COC1=CC(/C(C(N2CCN(CC2)C3=CC=C(C=C3)C)=O)=C\C4=CC(O)=C(C=C4)OC)=CC(OC)=C1OC
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Zhang H, et al. Design, synthesis of combretastatin A-4 piperazine derivatives as potential antitumor agents by inhibiting tubulin polymerization and inducing autophagy in HCT116 cells. Eur J Med Chem. 2024 Jun 5;272:116497. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ