Antitumor agent-162
Antitumor agent-162 (compound 52a) is a potent and orally active antitumor agent. Antitumor agent-162 shows cytotoxicity.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C26H19Cl2NO4
- 分子量:480.34
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Antitumor agent-162 (compound 52a) (0-5000 nM) shows cytotoxicity with IC50s of 63, 84 nM for Mut6, UTSW63 cells, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| route | T1/2 (h) | Cmax (ng/mL) | Tmax (h) | AUClast (ng*min/mL) | CL | kp (AUCbrain/AUCplasma) | |
| plasma | i.p. (10 mg/kg) | 234 | 1303 | 30 | 289860 | 0.13 | - |
| i.v. (5 mg/kg) | 189 | 12000 | 5 | 885630 | 0.14 | - | |
| p.o. (20 mg/kg) | 208 | 3404 | 30 | 1387613 | 0.14 | - | |
| brain | i.p. (10 mg/kg) | 182 | 2526 | 90 | 720503 | - | 2.49 |
| i.v. (5 mg/kg) | 294 | 3257 | 5 | 767638 | - | 0.87 | |
| p.o. (20 mg/kg) | 254 | 2381 | 90 | 1774789 | - | 1.28 |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 480.34
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分子式 C26H19Cl2NO4
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SMILES
ClC1=CC(Cl)=CC(C(COC2=CC=C(C=C2)N3C(C4C(C5C6CC6C57C=CC47)C3=O)=O)=O)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Antitumor agent-162 関連分類
HY-162560 関連分類
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