Aramisulpride (Standard)
Aramisulpride (Standard) is the analytical standard of Aramisulpride (HY-109167). This product is intended for research and analytical applications. Aramisulpride (R-(+)-Amisulpride) is the R-isomer of Amisulpride (HY-14545). Aramisulpride is a 5-HT7 receptor antagonist with a Ki value of 22 nM. Aramisulpride is a D2/D3 receptor antagonist with a Ki value of 140 nM for D2R and a Ki value of 13.9 nM for D3R. Aramisulpride can be used in psychiatric research.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 71675-90-6
- 分子式: C17H27N3O4S
- 分子量:369.48
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
化学情報
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CAS 番号 71675-90-6
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分子量 369.48
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分子式 C17H27N3O4S
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SMILES
O=C(NC[C@@H]1N(CC)CCC1)C2=CC(S(=O)(CC)=O)=C(N)C=C2OC
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別名
(R)-Amisulpride (Standard); (R)-Esamisulpride (Standard); (R)-DAN 2163 (Standard)
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Vincent Grattan, et al. Antipsychotic Benzamides Amisulpride and LB-102 Display Polypharmacy as Racemates, S Enantiomers Engage Receptors D2 and D3, while R Enantiomers Engage 5-HT7. ACS Omega. 2019 Aug 15;4(9):14151-14154. [Content Brief]
[2]. Hopkins SC, et al. Discovery of Nonracemic Amisulpride to Maximize Benefit/Risk of 5-HT7 and D2 Receptor Antagonism for the Treatment of Mood Disorders. Clin Pharmacol Ther. 2021 Sep;110(3):808-815. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)