Bromo-PEG2-bromide
Based on 1 Customer Validation
Bromo-PEG2-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.25%
- CAS 番号: 31255-10-4
- 分子式: C6H12Br2O2
- 分子量:275.97
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 31255-10-4
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性状 Liquid (Density: 1.6777 g/cm3)
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分子量 275.97
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分子式 C6H12Br2O2
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Color Colorless to light yellow
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SMILES
BrCCOCCOCCBr
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (362.36 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (393 KB)
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- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6236 mL | 18.1179 mL | 36.2358 mL | 90.5896 mL |
| 5 mM | 0.7247 mL | 3.6236 mL | 7.2472 mL | 18.1179 mL | |
| 10 mM | 0.3624 mL | 1.8118 mL | 3.6236 mL | 9.0590 mL | |
| 15 mM | 0.2416 mL | 1.2079 mL | 2.4157 mL | 6.0393 mL | |
| 20 mM | 0.1812 mL | 0.9059 mL | 1.8118 mL | 4.5295 mL | |
| 25 mM | 0.1449 mL | 0.7247 mL | 1.4494 mL | 3.6236 mL | |
| 30 mM | 0.1208 mL | 0.6039 mL | 1.2079 mL | 3.0197 mL | |
| 40 mM | 0.0906 mL | 0.4529 mL | 0.9059 mL | 2.2647 mL | |
| 50 mM | 0.0725 mL | 0.3624 mL | 0.7247 mL | 1.8118 mL | |
| 60 mM | 0.0604 mL | 0.3020 mL | 0.6039 mL | 1.5098 mL | |
| 80 mM | 0.0453 mL | 0.2265 mL | 0.4529 mL | 1.1324 mL | |
| 100 mM | 0.0362 mL | 0.1812 mL | 0.3624 mL | 0.9059 mL |