952588-17-9
952588-17-9
Chemical Structure
InhA-IN-7
- CAS 番号: 952588-17-9
- Formula:C17H18Cl2O2
- Molecular Weight:325.23
InChIKey: CODNLKSZUDXSLW-UHFFFAOYSA-N
SMILES: ClC1=CC=C(C(Cl)=C1)OC2=CC=C(CCC(C)C)C=C2O
Biological Activity: InhA-IN-7 (Compound 11) is a Triclocan (HY-B1119) derivative with inhibitory activity towards enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. InhA-IN-7 inhibits proliferations of Mycobacterium tuberculosis wildtype and mutant strains with MICs ranging from 19 to 75 μM[1].
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InhA-IN-7 | InhA-IN-7 (Compound 11) is a Triclocan (HY-B1119) derivative with inhibitory activity towards enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. InhA-IN-7 inhibits proliferations of Mycobacterium tuberculosis wildtype and mutant strains with MICs ranging from 19 to 75 μM. | |||||||||||||||||||||
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References
Keywords
