CDC14A/B-IN-2
CDC14A/B-IN-2, phosphotyrosine mimetic, is a competitive human CDC14A/B phosphatase inhibitor with IC50 values of 10.4 and 11.2 μM, and Ki values of 5.8 and 7.3 μM. CDC14A/B-IN-2 shows at least 20-fold selectivity over other protein tyrosine phosphatases. CDC14A/B-IN-2 can be used for the research of cancer.
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- CAS 番号: 3048654-21-0
- 分子式: C13H9F2O4P
- 分子量:298.18
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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hCDC14A 10.4 μM (IC50) |
hCDC14B 11.2 μM (IC50) |
hCDC14A 5.8 μM (Ki) |
hCDC14B 7.3 μM (Ki) |
CDC14A/B-IN-2 (Compound 9) (10 min) competitively inhibits recombinant human CDC14A and CDC14B phosphatases with IC50 values of 10.4 and 11.2 μM, and Ki values of 5.8 and 7.3 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3048654-21-0
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分子量 298.18
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分子式 C13H9F2O4P
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SMILES
O=P(O)(C(F)(C1=C2C3=C(C=CC=C3)OC2=CC=C1)F)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)