Cinnamic acid sodium
Based on 3 publication(s) in Google Scholar
Cinnamic acid sodium is a orally active naturally occurring aromatic fatty acid of low toxicity. Cinnamic acid sodium shows neuroprotective and anti-inflammatory effects.
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- CAS 番号: 538-42-1
- 分子式: C9H7NaO2
- 分子量:170.14
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Cinnamic acid sodium
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生物活性
Cinnamic acid sodium (0.05, 0.4, 3.2 mM; 6, 12, 24 h) induces apoptosis in HT-144 cells in 3.2 mM at 24 h[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:NGM, HT-144 cells
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Concentration:0.05, 0.4, 3.2 mM
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Incubation Time:6, 12, 24 h
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Result:Induced apoptosis in HT-144 cells in 3.2 mM at 24 h, no effect apoptosis in NGM cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:6-8 weeks, C57BL/6 mice (18 mg/kg MPTP-HCl, i.p.; at 2-h intervals for 4 times)[1]
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Dosage:100 mg/kg
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Administration:Gavage; starting from 3 h after the last injection of MPTP
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Result:Protected nigral TH levels, protected striatal innervation and neurotransmitters, restored locomotor deficit, increased the activation of Peroxisome Proliferator-Activated Receptor alpha (PPARα) in primary mouse astrocytes, protected striatal TH via PPARα.
化学情報
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CAS 番号 538-42-1
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分子量 170.14
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分子式 C9H7NaO2
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SMILES
O=C(O[Na])/C=C/C1=CC=CC=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (3)
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Journal Impact Factor
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Most Recent
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J Neurosci
2025 Aug 27;45(35):e0523252025. PMID: 40769725 -
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純度とドキュメンテーション
参考文献
[1]. Prorok T, et al. Cinnamic Acid Protects the Nigrostriatum in a Mouse Model of Parkinson's Disease via Peroxisome Proliferator-Activated Receptorα. Neurochem Res. 2019 Apr;44(4):751-762. [Content Brief]
[3]. Niero EL, et al. Cinnamic acid induces apoptotic cell death and cytoskeleton disruption in human melanoma cells. J Exp Clin Cancer Res. 2013 May 23;32(1):31. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Cinnamic acid sodium 関連分類
HY-130762 関連分類
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