COX-2-IN-65
COX-2-IN-65 is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 10.24 μM. COX-2-IN-65 inhibits Staphylococcus aureus and Escherichia coli growth. COX-2-IN-65 scavenges reactive oxygen species (ROS). COX-2-IN-65 can be used for the researches of bacterial infections and inflammation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1408337-43-8
- 分子式: C18H14ClNO3
- 分子量:327.76
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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COX-2 10.24 μM (IC50) |
COX-2-IN-65 (Compound 4h) selectively inhibits recombinant human COX-2 with an IC50 of 10.24 μM and a selectivity index of 3.09[1].
COX-2-IN-65 inhibits 30% of Staphylococcus aureus growth and 90% of Escherichia coli growth[1].
COX-2-IN-65 (50-100 μg/mL) shows ROS-scavenging capacity (37-61%)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1408337-43-8
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分子量 327.76
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分子式 C18H14ClNO3
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SMILES
CCOC(C1=C2N(C(C(C3=CC=CC=C3)=O)=C1)C=CC(Cl)=C2)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)