Direct red 254
Based on 1 Customer Validation
Direct Red 254 is a bisazo dye for textile applications. Direct Red 254 can be used for amyloid tissue staining in basic research on neurodegenerative diseases (e.g., Alzheimer's disease).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 6300-50-1
- 分子式: C22H15N5Na2O7S2
- 分子量:571.49
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
Direct Red 254 (1% (w/v)) stains amyloid-like synthetic peptides and induces birefringence in vitro: some peptide fragments with amyloid-like properties (e.g., peptide fragment N14) exhibit green birefringence under polarized light after staining. This is a typical characteristic of amyloid deposits[1].
Direct Red 254 can be effectively biodecolorized, and its decolorization efficiency is affected by its molecular structure and aggregation behavior in aqueous solution[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 6300-50-1
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性状 Solid
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分子量 571.49
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分子式 C22H15N5Na2O7S2
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Color black
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SMILES
O=S(C1=C(N=NC2=CC=C(N=NC3=CC=C(S(=O)(O[Na])=O)C=C3)C=C2)C(O)=C4C=CC(N)=CC4=C1)(O[Na])=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Hilbich C, et al. Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11. J Biol Chem. 1993;268(35):26571-26577. [Content Brief]
[2]. Brás R, et al. Monoazo and diazo dye decolourisation studies in a methanogenic UASB reactor. J Biotechnol. 2005;115(1):57-66. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)