DSPE-PEG2000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10)
DSPE-PEG2000-LyP-1 is a PEG compound which composed of DSPE and a nine residue peptide (LyP-1) (HY-P2526). LyP-1 is a cyclic 9-amino-acids tumor homing peptide and selectively bind to p32 receptors overexpressed in various tumor-associated cells.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子量:2000 (Average)
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
DSPE (distearate phosphatidylethanolamine): Acts as a hydrophobic anchor. Its two long hydrophobic chains are stably embedded in the lipid bilayer of the nanocarrier.
PEG2000 (polyethylene glycol, molecular weight 2000 Da): Acts as a hydrophilic linker and cryptic layer. Provides long-cycle functionality and exposes active peptides on the nanoparticle surface.
CGNKRTRGC (Lyp-1): A cyclic nonapeptide formed by disulfide bonds between two cysteine residues at the N- and C-termini. CGNKRTRGC specifically recognizes and binds to neurociliaryin-1, which is highly expressed on the surface of tumor lymphatic endothelial cells and certain tumor cells.
DSPE-PEG2000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) enables active targeting and penetration of tumor tissue.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 2000 (Average)
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SMILES
[Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10)]C(CCOCCOC(NCCOP(OC[C@](COC(CCCCCCCCCCCCCCCCC)=O)([H])OC(CCCCCCCCCCCCCCCCC)=O)(O)=O)=O)=O.[n]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DSPE-PEG2000-Mal-Cys-CGNKRTRGC (Disulfide bridge: Cys2-Cys10) 関連分類
HY-172271A 関連分類
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