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FLT3-IN-31

FLT3-IN-31 (compound 10q) is a potent FLT3 inhibitor with IC50 values of 0.16, 2.4 nM for FLT3, FLT3-D835Y, resprctively. FLT3-IN-31 shows antiproliferation activity. FLT3-IN-31 decreases the protein expression of p-FLT3, P-STAT5, P-ERK. FLT3-IN-31 induces apoptosis and cell cycle arrest at G1 phase. FLT3-IN-31 shows antitumor activity.

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  • CAS 番号: 2290545-53-6
  • 分子式: C25H24FN5O
  • 分子量:429.49
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • FLT3-IN-31 Chemical Structure
    FLT3-IN-31 構造式
CAS 番号: 2290545-53-6
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  • FLT3-IN-31 Chemical Structure
    FLT3-IN-31 Chemical Structure
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  • FLT3-IN-31