Fmoc-NH-PEG8-NHS ester
Based on 1 Customer Validation
Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.0%
- CAS 番号: 1334170-03-4
- 分子式: C38H52N2O14
- 分子量:760.82
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保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1334170-03-4
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性状 Viscous Liquid
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分子量 760.82
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分子式 C38H52N2O14
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Color Colorless to light yellow
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SMILES
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON4C(CCC4=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (131.44 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3144 mL | 6.5719 mL | 13.1437 mL | 32.8593 mL |
| 5 mM | 0.2629 mL | 1.3144 mL | 2.6287 mL | 6.5719 mL | |
| 10 mM | 0.1314 mL | 0.6572 mL | 1.3144 mL | 3.2859 mL | |
| 15 mM | 0.0876 mL | 0.4381 mL | 0.8762 mL | 2.1906 mL | |
| 20 mM | 0.0657 mL | 0.3286 mL | 0.6572 mL | 1.6430 mL | |
| 25 mM | 0.0526 mL | 0.2629 mL | 0.5257 mL | 1.3144 mL | |
| 30 mM | 0.0438 mL | 0.2191 mL | 0.4381 mL | 1.0953 mL | |
| 40 mM | 0.0329 mL | 0.1643 mL | 0.3286 mL | 0.8215 mL | |
| 50 mM | 0.0263 mL | 0.1314 mL | 0.2629 mL | 0.6572 mL | |
| 60 mM | 0.0219 mL | 0.1095 mL | 0.2191 mL | 0.5477 mL | |
| 80 mM | 0.0164 mL | 0.0821 mL | 0.1643 mL | 0.4107 mL | |
| 100 mM | 0.0131 mL | 0.0657 mL | 0.1314 mL | 0.3286 mL |
Fmoc-NH-PEG8-NHS ester 関連分類
HY-126880 関連分類
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