FGF16 - fibroblast growth factor 16 Gene

Also Known as MF4; FGF-16

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 8823

About FGF16

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:77,447,389-77,457,278 (from NCBI)

This gene has 1 transcript (splice variant), 196 orthologues, 21 paralogues and is associated with 2 phenotypes. Low expression observed in reference dataset.

Summary

This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014]

FGF16 Products (1)

mRNA Protein Name
NM_003868.3 NP_003859.1 fibroblast growth factor 16

FGF16 Protein Structure

FGF

FGF: Fibroblast growth factor (2 - 96)

  • 0
  • 100
  • 116 a.a.
Protein Preferred Names Protein Names

fibroblast growth factor 16

  • metacarpal 4-5 fusion

FGF16 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
FGF16 O43320 HOOK2 Homo sapiens Q96ED9-2
Validated Y2H
32296183
Intra
FGF16 O43320 HOOK2 Homo sapiens Q96ED9-2
Y2H Prey Pooling
32296183
Intra
FGF16 O43320 HOOK2 Homo sapiens Q96ED9-2
Y2H Array
32296183
Intra
FGF16 O43320 CLP1 Homo sapiens Q92989
Validated Y2H
32296183
Intra
FGF16 O43320 MCC Homo sapiens P23508
Validated Y2H
32296183
Intra
FGF16 O43320 MCC Homo sapiens P23508
Y2H Array
32296183
Intra
FGF16 O43320 MCC Homo sapiens P23508
Y2H Prey Pooling
32296183
Intra
FGF16 O43320 INCA1 Homo sapiens Q0VD86
Validated Y2H
32296183
Intra
FGF16 O43320 INCA1 Homo sapiens Q0VD86
Y2H Array
32296183
Intra
FGF16 O43320 INCA1 Homo sapiens Q0VD86
Y2H Prey Pooling
32296183
Intra
FGF16 O43320 DVL3 Homo sapiens Q92997
Validated Y2H
32296183
Intra
FGF16 O43320 DVL3 Homo sapiens Q92997
Y2H Array
32296183
Intra
FGF16 O43320 DVL3 Homo sapiens Q92997
Y2H Prey Pooling
32296183
Intra
FGF16 O43320 PICK1 Homo sapiens Q9NRD5
Y2H Prey Pooling
32296183
Intra
FGF16 O43320 PICK1 Homo sapiens Q9NRD5
Y2H Array
32296183
Intra
FGF16 O43320 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
Intra
FGF16 O43320 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
FGF16 O43320 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
Intra
FGF16 O43320 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant FGF16 Proteins

製品番号 製品名 アクセッション番号 純度
HY-P7344 FGF-16 Protein, Human (CHO) O43320 (A2-R207) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700059AF Animal-Free FGF-16 Protein, Human (His) O43320 (A2-R207) ≥ 95%, as determined by reducing SDS-PAGE.

関連疾患

Diseases Alias
Metacarpal 4-5 Fusion

  • Syndactyly Type 8

  • MF4

  • Fusion Of Metacarpals 4 And 5

  • Metacarpals 4 And 5 Fusion

  • Metacarpal 4 5 Fusion
Syndactyly, Type Iii

  • Syndactyly Type 3

  • SDTY3

  • Ring And Little Finger Syndactyly

  • Syndactyly Of Fingers Iv And V

  • Syndactyly Of Fingers 4 And 5

  • Ringand Little Finger Syndactyly

  • Syndactyly Of Fingers Four And Five

  • Syndactyly Of The Ring And Little Finger

  • Sd3

  • Syndactyly 3

  • Syndactyly Type Iii

  • 4-5 Finger Syndactyly

  • Syndactyly, Type 3
Zygodactyly 1

  • Zd1

  • Zygodactyly Type 1

  • Sd1, Weidenreich Type

  • Sd1a

  • Syndactyly Type 1, Weidenreich Type

  • Syndactyly Type 1a

  • Zygodactyly, Weidenreich Type
Chromosome 2q35 Duplication Syndrome

  • Syndactyly

  • Syndactyly Type 1

  • Sdty1

  • Zygodactyly

  • Syndactyly, Type I

  • Sd1

  • Syndactyly, Type 1, With Or Without Craniosynostosis

  • Symphalangism

  • Non-Syndromic Syndactyly

  • Symphalangy

  • Webbing Of Digits

  • Syndactyly, Type 1
Syndactyly, Type Iv

  • Syndactyly Type 4

  • Polysyndactyly, Haas Type

  • SDTY4

  • Haas Type Syndactyly

  • Sd4

  • Polysyndactyly Type Haas

  • Syndactyly 4

  • Polysyndactyly Haas Type

  • Syndactyly Type Iv
Beare-Stevenson Cutis Gyrata Syndrome

  • Cutis Gyrata Syndrome Of Beare And Stevenson

  • Beare-Stevenson Syndrome

  • BSTVS

  • Cutis Gyrata-Acanthosis Nigricans-Craniosynostosis Syndrome

  • Beare Stevenson Syndrome

  • Cutis Gyrata - Acanthosis Nigricans - Craniosynostosis

  • Cutis Gyrata Syndrome Of Beare-Stevenson
Achondroplasia, Severe, With Developmental Delay And Acanthosis Nigricans

  • SADDAN

  • Saddan Dysplasia

  • Severe Achondroplasia With Developmental Delay And Acanthosis Nigricans

  • Severe Achondroplasia-Developmental Delay-Acanthosis Nigricans Syndrome

  • Ssb Syndrome

  • Skeleton Skin Brain Syndrome

  • Skeleton-Skin-Brain Syndrome

  • Achondroplasia
Poland Syndrome

  • Poland Anomaly

  • Poland Sequence

  • Poland Syndactyly

  • Poland'S Syndrome

  • Poland'S Anomaly

  • Poland'S Syndactyly

  • Acro-Pectoro-Renal Field Defect

  • Brachydactyly, Absent Pectoral Muscles And Agenesis/Hypoplasia Of Kidneys

  • Unilateral Defect Of Pectoralis Muscle And Syndactyly Of The Hand

  • Unilateral Defect Of Pectoralis Major And Syndactyly Of The Hand
Multiple Synostoses Syndrome

  • Symphalangism-Brachydactyly Syndrome

  • Deafness-Hermann Type Symphalangism Syndrome

  • Facio-Audio-Symphalangism

  • Hearing Loss-Hermann Type Symphalangism Syndrome

  • Wl Syndrome

  • Multiple Synostosis Syndrome
Crouzon Syndrome

  • Crouzon Craniofacial Dysostosis

  • Craniofacial Dysostosis

  • Cfd1

  • Craniofacial Dysostosis Type 1

  • Crouzon Disease

  • Crouzon'S Disease

  • Craniofacial Dysostosis, Type I

  • Craniofacial Dysarthrosis

  • Craniofacial Dysostosis Syndrome

  • CS

  • Craniofacial Dysostosis Type I

  • Vogt Cephalosyndactyly
Cardiomyopathy, Familial Hypertrophic, 1

  • Asymmetric Septal Hypertrophy

  • Familial Hypertrophic Cardiomyopathy

  • Hypertrophic Cardiomyopathy 1

  • CMH1

  • Hypertrophic Cardiomyopathy 19

  • CMH

  • Ventricular Hypertrophy, Hereditary

  • Ash

  • Hypertrophic Subaortic Stenosis, Idiopathic

  • Cardiomyopathy, Familial Hypertrophic

  • Cardiomyopathy, Hypertrophic, 1, Digenic

  • Cardiomyopathy, Familial Hypertrophic 1

  • Hcm

  • Hereditary Ventricular Hypertrophy

  • Idiopathic Hypertrophic Subaortic Stenosis

  • Hypertrophic Cardiomyopathy

  • Cardiomyopathy, Hypertrophic, Familial

  • Cardiomyopathy, Hypertrophic, 1

  • Familial Asymmetric Septal Hypertrophy

  • Heritable Hypertrophic Cardiomyopathy

  • Fhc

  • Cardiomyopathy, Hypertrophic, Familial, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS04892 FGF16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174706 Human FGF16 mRNA / Unkown
HY-RS20404 Fgf16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26913 Fgf16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Felis catus FGF16 VGNC VGNC:62248
Macaca mulatta FGF16 VGNC VGNC:72646
Rattus norvegicus FGF16 RGD RGD:71052
Bos taurus FGF16 VGNC VGNC:28973
Mus musculus FGF16 MGD MGI:1931627
Canis familiaris FGF16 VGNC VGNC:40843
Others FGF16 NCBI