HER2-IN-11
HER2-IN-11 is a psoralen derivative. HER2-IN-11 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-11 induces apoptosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C17H11NO6
- 分子量:325.27
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
HER2-IN-11 (50 µM) has phototoxicity against SK-BR-3 cells with the IC50 of 2.71 µM[1].
HER2-IN-11 (1-50 µM; 48 h) changes the morphology of the SK-BR-3 cells under UVA irradiation and increases the apoptotic index[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SK-BR-3 cells
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Concentration:1, 2.5, 5, 10, 20 and 50 µM
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Incubation Time:48 hours
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Result:Broken down cells into apoptotic bodies at higher concentrations (10, 20, and 50 µM) and cell shrinkage, plasma membrane blebbing at lower concentrations (1, 2.5, and 5 µM).
化学情報
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分子量 325.27
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分子式 C17H11NO6
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SMILES
O=C(C1=CC=CO1)NC(C2=C(OC=C2)C(OC)=C3O4)=C3C=CC4=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
HER2-IN-11 関連分類
HY-151118 関連分類
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