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ICMT-IN-35

ICMT-IN-35 (compound 10n) is a FTPA-triazole compound and ICMT inhibitor (IC50=0.8 μM). ICMT-IN-35 is taken up by mammalian cells and can prevent K-Ras membrane localization and induce K-Ras mislocalization. Furthermore, ICMT-IN-35 is selectively cytotoxic against ICMT+/+ MEF cells and has low micromolar activity (IC50=0.8 μM) against metastatic pancreatic cancer cell lines.

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  • 分子式: C25H29N3O2S
  • 分子量:435.58
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • ICMT-IN-35 Chemical Structure
    ICMT-IN-35 構造式
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  • ICMT-IN-35 Chemical Structure
    ICMT-IN-35 Chemical Structure
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  • ICMT-IN-35