Lenalidomide 5'-piperazine hydrochloride
Based on 1 Customer Validation
Lenalidomide 5'-piperazine hydrochloride can serve as a Cereblon ligand to recruit CRBN protein. Lenalidomide 5'-piperazine hydrochloride can be linked to target protein ligands via a linker to form PROTAC molecules, such as KI-CDK9d-32 (HY-173523).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.92%
- CAS 番号: 2222120-31-0
- 分子式: C17H21ClN4O3
- 分子量:364.83
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-L050
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E3 Ligase Ligand Library
HY-L128
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
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Molecular Glue-like Compound Library
HY-L918
生物活性
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Cereblon |
化学情報
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CAS 番号 2222120-31-0
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性状 Solid
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分子量 364.83
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分子式 C17H21ClN4O3
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Color White to off-white
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SMILES
O=C1NC(C(CC1)N2C(C3=CC=C(N4CCNCC4)C=C3C2)=O)=O.Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (274.10 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
純度とドキュメンテーション
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データシート (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7410 mL | 13.7050 mL | 27.4100 mL | 68.5251 mL |
| 5 mM | 0.5482 mL | 2.7410 mL | 5.4820 mL | 13.7050 mL | |
| 10 mM | 0.2741 mL | 1.3705 mL | 2.7410 mL | 6.8525 mL | |
| 15 mM | 0.1827 mL | 0.9137 mL | 1.8273 mL | 4.5683 mL | |
| 20 mM | 0.1371 mL | 0.6853 mL | 1.3705 mL | 3.4263 mL | |
| 25 mM | 0.1096 mL | 0.5482 mL | 1.0964 mL | 2.7410 mL | |
| 30 mM | 0.0914 mL | 0.4568 mL | 0.9137 mL | 2.2842 mL | |
| 40 mM | 0.0685 mL | 0.3426 mL | 0.6853 mL | 1.7131 mL | |
| 50 mM | 0.0548 mL | 0.2741 mL | 0.5482 mL | 1.3705 mL | |
| 60 mM | 0.0457 mL | 0.2284 mL | 0.4568 mL | 1.1421 mL | |
| 80 mM | 0.0343 mL | 0.1713 mL | 0.3426 mL | 0.8566 mL | |
| 100 mM | 0.0274 mL | 0.1371 mL | 0.2741 mL | 0.6853 mL |
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