Lyso Flipper-TR 29
Lyso Flipper-TR 29 is a Flipper probe that can label lysosomes. Lyso Flipper-TR 29 enters lysosomes and late endosomes by transient deprotonation to cross their membranes in neutral form.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2324152-35-2
- 分子式: C35H37N5O4S6
- 分子量:784.09
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Lyso Flipper-TR 29 enters lysosomes by transient deprotonation to diffuse in neutral form across the hydrophobic membrane, while its return to the cytosol is not possible because low pH≈5 within lysosomes prevents transient deprotonation. Lyso Flipper-TR 29 tracks also late endosomes, but fails to label early endosomes (EE) because their internal pH >6 is too high to prevent transient deprotonation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2324152-35-2
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分子量 784.09
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分子式 C35H37N5O4S6
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SMILES
CC1=C(C#N)SC(C2=C3C(C)=C(C4=C(C)C(SC5=C6SC(COCC7=CN(CCCCCCN8CCOCC8)N=N7)=C5C)=C6S4)S2)=C1S3(=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)